ID | 57822 |
フルテキストURL | |
著者 |
Ryuno, Hiroki
Graduate School of Pharmaceutical Sciences, The University of Tokyo
Nigo, Fuki
Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama University
Naguro, Isao
Graduate School of Pharmaceutical Sciences, The University of Tokyo
Sekimizu, Kazuhisa
Institute of Medical Mycology, Teikyo University
Kaito, Chikara
Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama University
ORCID
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抄録 | Staphylococcus aureus formed bacterial aggregates in the plasma fraction of the hemolymph of silkworm, the larva of Bombyx mori, in a growth-dependent manner. The addition of arabinose or galactose inhibited the formation of S. aureus aggregates in the silkworm plasma. Formation of the bacterial aggregates depended on S. aureus genes required for the synthesis of bacterial surface polysaccharides-ypfP and ltaA, which are involved in lipoteichoic acid synthesis, and the tagO gene, which is involved in wall teichoic acid synthesis. These findings suggest that S. aureus forms bacterial aggregates in the silkworm plasma via bacterial surface teichoic acids.
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発行日 | 2019-05-30
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出版物タイトル |
PLoS ONE
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巻 | 14巻
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号 | 5号
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出版者 | Public Library of Science
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開始ページ | e0217517
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ISSN | 1932-6203
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資料タイプ |
学術雑誌論文
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言語 |
英語
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OAI-PMH Set |
岡山大学
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著作権者 | Copyright: © 2019 Ryuno et al.
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論文のバージョン | publisher
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PubMed ID | |
DOI | |
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関連URL | isVersionOf https://doi.org/10.1371/journal.pone.0217517
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ライセンス | https://creativecommons.org/licenses/by/4.0/
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Citation | Ryuno H, Nigo F, Naguro I, Sekimizu K, Kaito C (2019) Staphylococcus aureus aggregation in the plasma fraction of silkworm hemolymph. PLoS ONE 14(5): e0217517. https://doi.org/10.1371/journal.pone.0217517
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助成機関名 |
日本学術振興会
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助成番号 | 15H04727
15H05783
19H03466
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