JaLCDOI 10.18926/AMO/55302
フルテキストURL 71_4_263.pdf
著者 Toyoshima, Atsuhiko| Yasuhara, Takao| Date, Isao|
抄録  To date, many animal studies have indicated the neuroprotective effects of mesenchymal stem cell (MSC) transplantation in ischemic stroke. Several clinical studies have also revealed the safety, feasibility, and neuroprotective effects in ischemic stroke patients. In this review, we present the main approaches of MSC transplantation in ischemic stroke, the mechanisms of MSC therapy, and the current clinical studies on MSC transplantation in ischemic stroke patients. We also explore the safety of MSC transplantation and conclude that MSC therapy will play an important role in the future treatment of ischemic stroke. The optimal timing, approach, and cell dose in the transplantation are important issues for successful clinical application.
キーワード mesenchymal stem cell ischemic stroke cell transplantation clinical trial
Amo Type Review
発行日 2017-08
出版物タイトル Acta Medica Okayama
71巻
4号
出版者 Okayama University Medical School
開始ページ 263
終了ページ 268
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 English
著作権者 CopyrightⒸ 2017 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 28824181
フルテキストURL Acta_Neurochir_159_7_1329.pdf
著者 Kidani, Naoya| Sugiu, Kenji| Hishikawa, Tomohito| Hiramatsu, Masafumi| Haruma, Jun| Nishihiro, Shingo| Takahashi, Yu| Date, Isao|
抄録 We present the case of a de novo vertebral artery dissecting aneurysm (VADA) after endovascular trapping of a ruptured VADA on the contralateral side. The first ruptured VADA involved the posterior inferior cerebellar artery, which was successfully treated by endovascular internal trapping using a stent. A follow-up study at 3 months revealed a de novo VADA on the contralateral side. The second VADA was successfully embolized using coils while normal arterial flow in the vertebral artery was preserved using a stent. Increased hemodynamic stress may cause the development of a de novo VADA on the contralateral side.
キーワード De novo aneurysm Hemodynamic stress Stent-assisted coil embolization Vertebral artery dissecting aneurysm
発行日 2017-07
出版物タイトル Acta Neurochirurgica
159巻
7号
出版者 Springer
開始ページ 1329
終了ページ 1333
ISSN 00016268
NCID AA0050885X
資料タイプ 学術雑誌論文
言語 English
OAI-PMH Set 岡山大学
著作権者 https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja
論文のバージョン author
PubMed ID 28493024
Web of Sience KeyUT 000403508400024
関連URL https://doi.org/10.1007/s00701-017-3204-2
JaLCDOI 10.18926/AMO/55201
フルテキストURL 71_3_191.pdf
著者 Kobayashi, Katsuhiro| Akiyama, Tomoyuki| Agari, Takashi| Sasaki, Tatsuya| Shibata, Takashi| Hanaoka, Yoshiyuki| Akiyama, Mari| Endoh, Fumika| Oka, Makio| Date, Isao|
抄録  Electroencephalogram (EEG) data include broadband electrical brain activity ranging from infra-slow bands (< 0.1 Hz) to traditional frequency bands (e.g., the approx. 10 Hz alpha rhythm) to high-frequency bands of up to 500 Hz. High-frequency oscillations (HFOs) including ripple and fast ripple oscillations (80-200 Hz and>200 / 250 Hz, respectively) are particularly of note due to their very close relationship to epileptogenicity, with the possibility that they could function as a surrogate biomarker of epileptogenicity. In contrast, physiological high-frequency activity plays an important role in higher brain functions, and the differentiation between pathological / epileptic and physiological HFOs is a critical issue, especially in epilepsy surgery. HFOs were initially recorded with intracranial electrodes in patients with intractable epilepsy as part of a long-term invasive seizure monitoring study. However, fast oscillations (FOs) in the ripple and gamma bands (40-80 Hz) are now noninvasively detected by scalp EEG and magnetoencephalography, and thus the scope of studies on HFOs /FOs is rapidly expanding.
キーワード fast oscillations, epilepsy electroencephalogram time-frequency analysis
Amo Type Review
発行日 2017-06
出版物タイトル Acta Medica Okayama
71巻
3号
出版者 Okayama University Medical School
開始ページ 191
終了ページ 200
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 English
著作権者 CopyrightⒸ 2017 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 28655938
JaLCDOI 10.18926/AMO/54987
フルテキストURL 71_2_179.pdf
著者 Nosaka, Nobuyuki| Tsukahara, Kohei| Knaup, Emily| Yabuuchi, Toshihiko| Kikkawa, Tomonobu| Fujii, Yosuke| Yashiro, Masato| Yasuhara, Takao| Okada, Ayumi| Ugawa, Toyomu| Nakao, Atsunori| Tsukahara, Hirokazu| Date, Isao|
抄録 Newly published clinical practice guidelines recommend intracranial pressure (ICP) monitoring in critical care for the management of pediatric acute encephalopathy (pAE), but the utility of ICP monitoring for pAE has been poorly studied. We recently performed direct ICP monitoring for two patients. We observed that although the direct ICP monitoring had clinical benefits with less body weight gain and no vasopressor use in both cases, this monitoring technique is still invasive. Future studies should determine the utility of non-invasive ICP monitoring systems in pAE to further improve the quality of intensive-care management.
キーワード cerebral perfusion encephalopathy child intracranial pressure neurological intensive care
Amo Type Short Communication
発行日 2017-04
出版物タイトル Acta Medica Okayama
71巻
2号
出版者 Okayama University Medical School
開始ページ 179
終了ページ 180
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 English
著作権者 CopyrightⒸ 2017 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 28420900
JaLCDOI 10.18926/AMO/54813
フルテキストURL 70_6_493.pdf
著者 Yasuhara, Takao| Kuwahara, Ken| Sasada, Susumu| Toyoshima, Atsuhiko| Morimoto, Jun| Kin, Kyohei| Manabe, Hiroaki| Miyoshi, Yasuyuki| Kusumegi, Akira| Takahashi, Yuichiro| Ito, Kiyoshi| Date, Isao|
抄録 Unexpected injuries can have a profound effect on a surgeonʼs performance and thus on patients and surgical departments. Here we describe a technique for performing surgery in the standing position, as done by a surgeon with an Achilles tendon rupture. During his prescribed 45-day non-weight-bearing period for the left ankle after surgery for an Achilles tendon rupture, the surgeon was able to participate in 15 surgeries as an operator or assistant, due to his use of a combination of injured-leg genuflection on a stool and a ʻSurgical Body Supportʼ device. Similarly injured surgeons may benefit from such support.
キーワード Achilles tendon rupture electromyogram genuflection injured leg standing position
Amo Type Short Communication
発行日 2016-12
出版物タイトル Acta Medica Okayama
70巻
6号
出版者 Okayama University Medical School
開始ページ 493
終了ページ 496
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 English
著作権者 CopyrightⒸ 2016 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 28003675
JaLCDOI 10.18926/AMO/54497
フルテキストURL 70_4_229.pdf
著者 Hishikawa, Tomohito| Sugiu, Kenji| Date, Isao|
抄録 About 5 decades have passed since the concept of moyamoya disease (MMD) was established in Japan. In that time, many clinical MMD studies have been performed from several different points of view, such as epidemiology, pathophysiology, surgical procedures, and prognosis. In addition, rapid developments in MMD genetic analysis have occurred. In light of all this activity, clinicians must continually update their knowledge of MMD in order to improve the prognosis of MMD patients. In this review article, we summarize the clinical MMD studies and introduce cutting-edge findings regarding MMD.
キーワード clinical research moyamoya disease
Amo Type Review
発行日 2016-08
出版物タイトル Acta Medica Okayama
70巻
4号
出版者 Okayama University Medical School
開始ページ 229
終了ページ 236
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 English
著作権者 CopyrightⒸ 2016 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 27549666
Web of Sience KeyUT 000384748600001
Sort Key 14
タイトル(別表記) Hosting the 18th JASMEE Academic Meeting in Okayama
フルテキストURL 128_69.pdf
著者 伊達 勲|
備考 学会報告(Meeting Reports)
出版物タイトル 岡山医学会雑誌
発行日 2016-04-01
128巻
1号
出版者 岡山医学会
出版者(別表記) Okayama Medical Association
開始ページ 69
終了ページ 70
ISSN 0030-1558
NCID AN00032489
資料タイプ 一般雑誌記事
関連URL isVersionOf https://doi.org/10.4044/joma.128.69
言語 Japanese
著作権者 Copyright (c) 2016 岡山医学会
論文のバージョン publisher
査読 有り
DOI 10.4044/joma.128.69
NAID 120005752921
Eprints Journal Name joma
Sort Key 17
タイトル(別表記) Hosting the 16th Annual Meeting of the Japanese Society for Normal Pressure Hydrocephalus
フルテキストURL 127_259.pdf
著者 伊達 勲|
備考 学会報告(Meeting Reports)
出版物タイトル 岡山医学会雑誌
発行日 2015-12-01
127巻
3号
出版者 岡山医学会
出版者(別表記) Okayama Medical Association
開始ページ 259
終了ページ 260
ISSN 0030-1558
NCID AN00032489
資料タイプ 一般雑誌記事
関連URL isVersionOf https://doi.org/10.4044/joma.127.259
言語 Japanese
著作権者 Copyright (c) 2015 岡山医学会
論文のバージョン publisher
査読 有り
DOI 10.4044/joma.127.259
NAID 130005116806
Eprints Journal Name joma
著者 Onishi, Manabu| Kurozumi, Kazuhiko| Ichikawa, Tomotsugu| Michiue, Hiroyuki| Fujii, Kentaro| Ishida, Joji| Shimazu, Yosuke| Chiocca, E Antonio| Kaur, Balveen| Date, Isao|
発行日 2013-04-15
出版物タイトル SpringerPlus
2巻
資料タイプ 学術雑誌論文
著者 Ishida, Joji| Onishi, Manabu| Kurozumi, Kazuhiko| Ichikawa, Tomotsugu| Fujii, Kentaro| Shimazu, Yosuke| Oka, Tetsuo| Date, Isao|
発行日 2014-04
出版物タイトル Translational Oncology
7巻
2号
資料タイプ 学術雑誌論文
著者 Wakamori, Takaaki| Agari, Takashi| Yasuhara, Takao| Kameda, Masahiro| Kondo, Akihiko| Shinko, Aiko| Sasada, Susumu| Sasaki, Tatsuya| Furuta, Tomohisa| Date, Isao|
発行日 2014-04
出版物タイトル Parkinsonism and Related Disorders
20巻
4号
資料タイプ 学術雑誌論文
著者 Fujii, K| Kurozumi, K| Ichikawa, T| Onishi, M| Shimazu, Y| Ishida, J| Chiocca, EA| Kaur, B| Date, I|
発行日 2013-08
出版物タイトル Cancer Gene Therapy
20巻
8号
資料タイプ 学術雑誌論文
著者 Itami, Hisakazu| Tokunaga, Koji| Okuma, Yu| Hishikawa, Tomohito| Sugiu, Kenji| Ida, Kentaro| Date, Isao|
発行日 2013-09
出版物タイトル Neuroradiology
55巻
9号
資料タイプ 学術雑誌論文
著者 Tayra, Judith Thomas| Kameda, Masahiro| Yasuhara, Takao| Agari, Takashi| Kadota, Tomohito| Wang, Feifei| Kikuchi, Yoichiro| Liang, Hanbai| Shinko, Aiko| Wakamori, Takaaki| Vcelar, Brigitta| Weik, Robert| Date, Isao|
発行日 2013-03-28
出版物タイトル Brain Research
1502巻
資料タイプ 学術雑誌論文
著者 伊達 勲|
発行日 2013-08-01
出版物タイトル 岡山医学会雑誌
125巻
2号
資料タイプ 一般雑誌記事
著者 大熊 佑| 劉 克約| 和気 秀徳| 春間 純| 吉野 正| 大塚 愛二| 高橋 英夫| 森 秀治| 西堀 正洋| 伊達 勲|
発行日 2013-08-01
出版物タイトル 岡山医学会雑誌
125巻
2号
資料タイプ 学術雑誌論文
著者 Onishi, Manabu| Ichikawa, Tomotsugu| Kurozumi, Kazuhiko| Fujii, Kentaro| Yoshida, Koichi| Inoue, Satoshi| Michiue, Hiroyuki| Chiocca, E. Antonio| Kaur, Balveen| Date, Isao|
発行日 2013-04
出版物タイトル Neuropathology
33巻
2号
資料タイプ 学術雑誌論文
著者 Maruo, Tomoko| Ichikawa, Tomotsugu| Kanzaki, Hirotaka| Inoue, Satoshi| Kurozumi, Kazuhiko| Onishi, Manabu| Yoshida, Koichi| Kambara, Hirokazu| Ouchida, Mamoru| Shimizu, Kenji| Tamaru, Seiji| Chiocca, E. Antonio| Date, Isao|
発行日 2013-06
出版物タイトル Neuropathology
33巻
3号
資料タイプ 学術雑誌論文
JaLCDOI 10.18926/AMO/50414
フルテキストURL 67_3_197.pdf
著者 Yasuhara, Takao| Takahashi, Yuichi| Kumamoto, Shinji| Nakahara, Masayuki| Yoneda, Kotaro| Niimura, Tatsuomi| Tanoue, Takashi| Kusumegi, Akira| Sennari, Takashi| Hijikata, Yasukazu| Manabe, Hiroaki| Miyoshi, Yasuyuki| Date, Isao| Ogawa, Koichi| Nishida, Kenki|
抄録 Some cases with lumbar degenerative diseases require multi-level fusion surgeries. At our institute, 27 and 4 procedures of 3- and 4-level fusion were performed out of a total 672 posterior lumbar interfusions (PLIFs) on patients with lumbar degenerative disease from 2005 to 2010. We present 2 osteoporotic patients who developed proximal vertebral body fracture after 4-level fusion. Both cases presented with gait disability for leg pain by degenerative lumbar scoliosis and canal stenosis at the levels of L1/2-4/5. After 4-level fusion using L1 as the upper instrumented vertebra, proximal vertebral body fractures were found along with the right pedicle fractures of L1 in both cases. One of these patients, aged 82 years, was treated as an outpatient using a hard corset for 24 months, but the fractures were exacerbated over time. In the other patient, posterolateral fusion was extended from Th10 to L5. Both patients can walk alone and have been thoroughly followed up. In both cases, the fracture of the right L1 pedicle might be related to the subsequent fractures and fusion failure. In consideration of multi-level fusion, L1 should be avoided as an upper instrumented vertebra to prevent junctional kyphosis, especially in cases with osteoporosis and flat back posture.
キーワード degenerative lumbar scoliosis osteoporosis pedicle fracture posterior lumbar interbody fusion vertebral body fracture
Amo Type Case Report
発行日 2013-06
出版物タイトル Acta Medica Okayama
67巻
3号
出版者 Okayama University Medical School
開始ページ 197
終了ページ 202
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 English
著作権者 CopyrightⒸ 2013 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 23804144
Web of Sience KeyUT 000320747900010
著者 Iwado, Eiji| Ichikawa, Tomotsugu| Kosaka, Hiroshi| Otsuka, Shinji| Kambara, Hirokazu| Tamiya, Takashi| Kondo, Seiji| Date, Isao|
発行日 2012-12
出版物タイトル Neuropathology
32巻
6号
資料タイプ 学術雑誌論文