start-ver=1.4
cd-journal=joma
no-vol=112
cd-vols=
no-issue=2
article-no=
start-page=419
end-page=424
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2024
dt-pub=20240909
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Electrochemically assisted sol-gel deposition of bioactive gels for biomedical applications
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=So far, the sol-gel process has been available to prepare precursor gels of bioactive glasses with various compositions. In this report, we described a novel coating method of bioactive gels on a titanium substrate where the sol-gel transition is controlled by applying external electric fields. The application of a constant current of 10?mA/cm2 in an acidic sol containing pre-hydrolyzed tetraethoxysilane, calcium nitrate, and ammonium dihydrogen phosphate led to the deposition of gels on the titanium cathodes due to the generation of OH? by water electrolysis as a catalyst of the sol-gel transition. The obtained gels, which were characterized to be amorphous and consisted of Si, Ca, and P, covered the titanium substrates as a coating. The bioactivity of the gels deposited was confirmed by soaking in a simulated body fluid (SBF) up to 7 days, suggesting that the electrochemically assisted sol-gel process is promising for providing bioactive coatings on metallic implants.
en-copyright=
kn-copyright=

en-aut-name=YoshiokaTomohiko
en-aut-sei=Yoshioka
en-aut-mei=Tomohiko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=

en-aut-name=MiyamotoNaoki
en-aut-sei=Miyamoto
en-aut-mei=Naoki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=

en-aut-name=HayakawaSatoshi
en-aut-sei=Hayakawa
en-aut-mei=Satoshi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=

affil-num=1
en-affil=Biomaterials Laboratory, Faculty of Interdisciplinary Science and Engineering in Health Systems, Okayama University
kn-affil=

affil-num=2
en-affil=Graduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University
kn-affil=

affil-num=3
en-affil=Biomaterials Laboratory, Faculty of Interdisciplinary Science and Engineering in Health Systems, Okayama University
kn-affil=
en-keyword=Sol-gel-derived gels
kn-keyword=Sol-gel-derived gels
en-keyword=Coating
kn-keyword=Coating
en-keyword=Water electrolysis
kn-keyword=Water electrolysis
en-keyword=Bioactivity
kn-keyword=Bioactivity
en-keyword=SBF
kn-keyword=SBF
END

start-ver=1.4
cd-journal=joma
no-vol=2
cd-vols=
no-issue=
article-no=
start-page=37
end-page=39
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2022
dt-pub=20220331
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Activity Report of Research Group for Next-Generation Interdisciplinary Science and Engineering in Health Systems
kn-title=統合科学次世代研究会の活動報告
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=YoshiokaTomohiko
en-aut-sei=Yoshioka
en-aut-mei=Tomohiko
kn-aut-name=吉岡朋彦
kn-aut-sei=吉岡
kn-aut-mei=朋彦
aut-affil-num=1
ORCID=

en-aut-name=HikasaHaruka
en-aut-sei=Hikasa
en-aut-mei=Haruka
kn-aut-name=日笠晴香
kn-aut-sei=日笠
kn-aut-mei=晴香
aut-affil-num=2
ORCID=

affil-num=1
en-affil=Faculty of Interdisciplinary Science and Engineering in Health Systems, Okayama University
kn-affil=岡山大学大学院ヘルスシステム統合科学学域

affil-num=2
en-affil=Faculty of Interdisciplinary Science and Engineering in Health Systems, Okayama University
kn-affil=岡山大学大学院ヘルスシステム統合科学学域
END

start-ver=1.4
cd-journal=joma
no-vol=292
cd-vols=
no-issue=
article-no=
start-page=110325
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2021
dt-pub=202103
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Crystallization characteristics of amorphous trehalose dried from alcohol
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Trehalose forms a glass that can be used to preserve labile substances under desiccation. The crystallization characteristics, namely crystallization temperature (Tcry) and isothermal crystallization behavior of amorphous trehalose, dried from alcohol (methanol, ethanol), was analyzed and the results were compared with those for the amorphous trehalose freeze-dried from water. The use of alcohol as a solvent lowered the Tcry from 184 ± 6 °C for the case of an aqueous solvent to 103 ± 5 °C/methanol and 120 ± 8 °C/ethanol. The formation of multiple forms of crystals and partial melting were suggested by the thermal analysis. Isothermal crystallization experiments showed that the alcohol-originated amorphous trehalose was eventually exclusively converted into β-form crystals. The induction period (tind) before the start of isothermal crystallization was markedly shortened when alcohol was used as the solvent compared to water. The tind values for various amorphous sugar samples including the alcohol-originated ones could be correlated with difference between Tcry and the sample temperature.
en-copyright=
kn-copyright=

en-aut-name=SekitohTakanari
en-aut-sei=Sekitoh
en-aut-mei=Takanari
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=

en-aut-name=OkamotoTakashi
en-aut-sei=Okamoto
en-aut-mei=Takashi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=

en-aut-name=FujiokaAkiho
en-aut-sei=Fujioka
en-aut-mei=Akiho
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=

en-aut-name=YoshiokaTomohiko
en-aut-sei=Yoshioka
en-aut-mei=Tomohiko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=

en-aut-name=TeruiShinji
en-aut-sei=Terui
en-aut-mei=Shinji
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=

en-aut-name=ImanakaHiroyuki
en-aut-sei=Imanaka
en-aut-mei=Hiroyuki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=

en-aut-name=IshidaNaoyuki
en-aut-sei=Ishida
en-aut-mei=Naoyuki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=7
ORCID=

en-aut-name=ImamuraKoreyoshi
en-aut-sei=Imamura
en-aut-mei=Koreyoshi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=8
ORCID=

affil-num=1
en-affil=Division of Chemistry and Biochemistry, Graduate School of Natural Science and Technology, Okayama University
kn-affil=

affil-num=2
en-affil=Division of Chemistry and Biochemistry, Graduate School of Natural Science and Technology, Okayama University
kn-affil=

affil-num=3
en-affil=Division of Chemistry and Biochemistry, Graduate School of Natural Science and Technology, Okayama University
kn-affil=

affil-num=4
en-affil=Graduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University
kn-affil=

affil-num=5
en-affil=Graduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University
kn-affil=

affil-num=6
en-affil=Division of Chemistry and Biochemistry, Graduate School of Natural Science and Technology, Okayama University
kn-affil=

affil-num=7
en-affil=Division of Chemistry and Biochemistry, Graduate School of Natural Science and Technology, Okayama University
kn-affil=

affil-num=8
en-affil=Division of Chemistry and Biochemistry, Graduate School of Natural Science and Technology, Okayama University
kn-affil=
en-keyword=Trehalose
kn-keyword=Trehalose
en-keyword=Crystallization
kn-keyword=Crystallization
en-keyword=Anhydrous crystal
kn-keyword=Anhydrous crystal
en-keyword=Methanol
kn-keyword=Methanol
en-keyword=Vacuum foam drying
kn-keyword=Vacuum foam drying
END

start-ver=1.4
cd-journal=joma
no-vol=7
cd-vols=
no-issue=1
article-no=
start-page=90
end-page=100
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2019
dt-pub=20190211
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Accelerated induction of in vitro apatite formation by parallel alignment of hydrothermally oxidized titanium substrates separated by sub-millimeter gaps
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract= Although autoclaving is a common sterilization method for biomedical devices, the ability to induce deposition of apatite particles on hydrothermally treated titanium is still not fully realized. This is because the induction ability is too weak to be evaluated via in vitro apatite formation in Kokubo's simulated body fluid (SBF) by the conventional immersion method, i.e. using samples with open and smooth surface. This study reports on the surface structure of hydrothermally treated titanium and the ability to induce deposition of apatite particles on the surface of parallel confined spaces separated by sub-millimeter gaps in Kokubo's SBF. Thin-film X-ray diffraction and analyses using Fourier transform infra-red (FT-IR) spectroscopy and Raman spectroscopy revealed that a nano-crystalline anatase-type titanium oxide layer was formed on titanium substrates after hydrothermal treatment at 150 degrees C for 2 h. When growth of the titanium oxide layer was moderately suppressed, the hydrothermally treated titanium surface exhibited a characteristic interference color, silver or gold, which does not impair the esthetic appearance of the titanium-based implant. The ability to induce deposition of apatite particles on hydrothermally treated titanium was remarkably amplified by parallel alignment of substrates separated by sub-millimeter gaps.
en-copyright=
kn-copyright=

en-aut-name=HayakawaSatoshi
en-aut-sei=Hayakawa
en-aut-mei=Satoshi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=

en-aut-name=OkamotoKeigo
en-aut-sei=Okamoto
en-aut-mei=Keigo
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=

en-aut-name=YoshiokaTomohiko
en-aut-sei=Yoshioka
en-aut-mei=Tomohiko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=

affil-num=1
en-affil=Graduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University
kn-affil=

affil-num=2
en-affil=Biomaterials Laboratory, Graduate School of Natural Science and Technology, Okayama University
kn-affil=

affil-num=3
en-affil=Graduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University
kn-affil=
en-keyword=Titanium substrate
kn-keyword=Titanium substrate
en-keyword=apatite deposition
kn-keyword=apatite deposition
en-keyword=simulated body fluid
kn-keyword=simulated body fluid
en-keyword=parallel alignment
kn-keyword=parallel alignment
en-keyword=titania layer
kn-keyword=titania layer
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2019
dt-pub=20191202
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Comparative study of in vitro apatite-forming abilities of highly ordered rutile nanorod arrays fabricated on cpTi and Ti6Al4V alloys
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract= The surfaces of commercially available pure titanium (cpTi) and Ti6Al4V alloy specimens were modified to form highly ordered rutile nanorod arrays by chemical treatment and subsequent aging treatment. The densities of the rutile rods were (1.04 +/- 0.06) x10(3) and (0.70 +/- 0.10) x10(3) mu m(-2) for the cpTi and Ti6Al4V alloy specimens, respectively. Both the rutile nanorod arrays on the cpTi and Ti6Al4V alloy specimens deposited apatite particles when soaked in simulated body fluid (SBF) for one day. After soaking for various other periods, scanning electron microscopy images and thin-film X-ray diffraction patterns of these specimens showed that the cpTi specimens exhibited a superior rate of apatite nucleation and favored the formation of numerous apatite particles with larger diameter. This superior apatite-forming ability of the cpTi specimens can be attributed to the dense, thick titania layers with higher rutile nanorod density on their surfaces.
en-copyright=
kn-copyright=

en-aut-name=LiuXingzhu
en-aut-sei=Liu
en-aut-mei=Xingzhu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=

en-aut-name=YoshiokaTomohiko
en-aut-sei=Yoshioka
en-aut-mei=Tomohiko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=

en-aut-name=HayakawaSatoshi
en-aut-sei=Hayakawa
en-aut-mei=Satoshi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=

affil-num=1
en-affil=Biomaterials Laboratory, Graduate School of Natural Science and Technology, Okayama University
kn-affil=

affil-num=2
en-affil=Biomaterials Laboratory, Graduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University
kn-affil=

affil-num=3
en-affil=Biomaterials Laboratory, Graduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University
kn-affil=
en-keyword=Rutile
kn-keyword=Rutile
en-keyword=nanorod arrays
kn-keyword=nanorod arrays
en-keyword=apatite
kn-keyword=apatite
en-keyword=rod density
kn-keyword=rod density
END