ID | 47085 |
フルテキストURL | |
タイトル(別表記) | Significance of reduction surgery in multidisciplinary treatment of advanced hepatocellular carcinoma with multiple intrahepatic metastases : A case report
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著者 |
佐藤 太祐
岡山大学大学院医歯薬学総合研究科 消化器外科学
楳田 祐三
岡山大学大学院医歯薬学総合研究科 消化器外科学
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抄録 | We report a case of advanced HCC with multiple intrahepatic metastases who obtained long-term survival by reductive hepatic resection as part of a multidisciplinary treatment. The patient was a 75-year-old man who had HCC, 13.5 cm in diameter in the right lobe of the liver with multiple intrahepatic metastases around the main tumor and 7 intrahepatic metastases in the left lobe of the liver. The large main tumor and intrahepatic metastases around the main tumor were initially resected by right lobectomy as reduction surgery. Transcatheter arterial chemoembolization (TACE) with epirubicin for intrahepatic metastases in the remnant liver was started 1 month after initial hepatectomy and repeated every 3 months. Twelve months after initial hepatectomy, lung metastases appeared, so we started systemic chemotherapy with 5-fluorouracil (5-FU) and cisplatin (CDDP). In addition, we changed epirubicin to CDDP for TACE. Despite this combination therapy, 20 months after the initial hepatectomy, the lung metastases showed an increase in size. We decided to discontinue systemic chemotherapy and administer sorafenib. The patient was alive without progression of intrahepatic metastasis and lung metastasis more than 26 months after the initial hepatectomy.
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キーワード | 進行肝細胞癌 (advanced hepatocellular carcinoma)
減量手術 (reduction surgery)
肝動脈塞栓療法 (transcatheter arterial chemoembolization : TACE)
ソラフェニブ (sorafenib)
集学的治療 (multidisciplinary treatment)
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備考 | 症例報告 (Case Report)
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発行日 | 2011-12-01
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出版物タイトル |
岡山医学会雑誌
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出版物タイトル(別表記) | Journal of Okayama Medical Association
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巻 | 123巻
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号 | 3号
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出版者 | 岡山医学会
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出版者(別表記) | Okayama Medical Association
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開始ページ | 213
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終了ページ | 216
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ISSN | 0030-1558
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NCID | AN00032489
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資料タイプ |
学術雑誌論文
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関連URL | http://www.okayama-u.ac.jp/user/oma/
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言語 |
日本語
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著作権者 | Copyright (c) 2011 岡山医学会
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論文のバージョン | publisher
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査読 |
有り
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DOI | |
Eprints Journal Name | joma
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