山崎泰史

Application of convolutional neural networks for evaluating the depth of invasion of early gastric cancer based on endoscopic images

フルテキストURL	fulltext20211210-1.pdf
著者	Hamada, Kenta\| Kawahara, Yoshiro\| Tanimoto, Takayoshi\| Ohto, Akimitsu\| Toda, Akira\| Aida, Toshiaki\| Yamasaki, Yasushi\| Gotoda, Tatsuhiro\| Ogawa, Taiji\| Abe, Makoto\| Okanoue, Shotaro\| Takei, Kensuke\| Kikuchi, Satoru\| Kuroda, Shinji\| Fujiwara, Toshiyoshi\| Okada, Hiroyuki\|
キーワード	Artificial intelligence convolutional neural network early gastric cancer endoscopic image invasion depth
備考	This is the peer reviewed version of the following article: [Hamada, K., Kawahara, Y., Tanimoto, T., Ohto, A., Toda, A., Aida, T., Yamasaki, Y., Gotoda, T., Ogawa, T., Abe, M., Okanoue, S., Takei, K., Kikuchi, S., Kuroda, S., Fujiwara, T., and Okada, H. (2021) Application of convolutional neural networks for evaluating the depth of invasion of early gastric cancer based on endoscopic images, Journal of Gastroenterology and Hepatology], which has been published in final form at [https://doi.org/10.1111/jgh.15725]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages there of by third parties from platforms, services and websites other than Wiley Online Library must be prohibited.\|
発行日	2021-11-25
出版物タイトル	Journal of Gastroenterology and Hepatology
出版者	Wiley
開始ページ	1
ISSN	0815-9319
NCID	AA10727383
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2021 Journal of Gastroenterology and Hepatology Foundation and John Wiley & Sons Australia, Ltd
論文のバージョン	author
PubMed ID	34713495
DOI	10.1111/jgh.15725
Web of Science KeyUT	000722466600001
関連URL	isVersionOf https://doi.org/10.1111/jgh.15725

Berberine improved experimental chronic colitis by regulating interferon-gamma- and IL-17A-producing lamina propria CD4(+) T cells through AMPK activation

フルテキストURL	SR9_1_11934.pdf
著者	Takahara, Masahiro\| Takaki, Akinobu\| Hiraoka, Sakiko\| Adach, Takuya\| Shimomura, Yasuyuki\| Matsushita, Hiroshi\| Nguyen Tien Thi Thuy\| Koike, Kazuko\| Ikeda, Airi\| Takashima, Shiho\| Yamasaki, Yasushi\| Inokuchi, Toshihiro\| Kinugasa, Hideaki\| Sugihara, Yusaku\| Harada, Keita\| Eikawa, Shingo\| Morita, Hidetoshi\| Udono, Heiichiro\| Okada, Hiroyuki\|
発行日	2019-8-15
出版物タイトル	Scientific Reports
巻	9巻
出版者	Nature Publishing Group
開始ページ	11934
ISSN	2045-2322
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2019
論文のバージョン	publisher
PubMed ID	31417110
DOI	10.1038/s41598-019-48331-w
Web of Science KeyUT	000480680800048
関連URL	isVersionOf https://doi.org/10.1038/s41598-019-48331-w

Clinicopathological Characteristics of Superficial Barrett's Adenocarcinoma in a Japanese Population: A Retrospective, Multicenter Study

フルテキストURL	fulltext.pdf
著者	Hamada, Kenta\| Kanzaki, Hiromitsu\| Miyahara, Koji\| Nakagawa, Masahiro\| Mouri, Hirokazu\| Mizuno, Motowo\| Takahashi, Sakuma\| Hori, Shinichiro\| Nasu, Junichiro\| Tsuzuki, Takao\| Miyaike, Jiro\| Takenaka, Ryuta\| Yamauchi, Kenji\| Kobayashi, Sayo\| Toyokawa, Tatsuya\| Inoue, Masafumi\| Nishimura, Mamoru\| Matsubara, Minoru\| Tomoda, Jun\| Yamasaki, Yasushi\| Tanaka, Takehiro\| Shirakawa, Yasuhiro\| Kawahara, Yoshiro\| Fujiwara, Toshiyoshi\| Okada, Hiroyuki\| Okayama Gut Study Group\|
キーワード	Barrett's adenocarcinoma endoscopic resection long -segment Barrett's esophagus metachronous lesion short -segment Barrett's esophagus surgery
発行日	2022-04-15
出版物タイトル	INTERNAL MEDICINE
巻	61巻
号	8号
出版者	The Japanese Society of Internal Medicine
開始ページ	1115
終了ページ	1123
ISSN	0918-2918
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2022 The Japanese Society of Internal Medicine
論文のバージョン	publisher
PubMed ID	35431302
DOI	10.2169/internalmedicine.6942-20
Web of Science KeyUT	000789463700001
関連URL	isVersionOf https://doi.org/10.2169/internalmedicine.6942-20

Continued Aspirin Treatment May Be a Risk Factor of Delayed Bleeding after Gastric Endoscopic Submucosal Dissection under Heparin Replacement: A Retrospective Multicenter Study

フルテキストURL	fulltext.pdf
著者	Hamada, Kenta\| Kanzaki, Hiromitsu\| Inoue, Masafumi\| Ishiyama , Shuhei\| Yamauchi, Kenji\| Miyahara, Koji\| Toyokawa, Tatsuya\| Tsuzuki, Takao\| Miyaike, Jiro\| Matsubara, Minoru\| Takahashi, Sakuma\| Nishimura, Mamoru\| Takenaka, Ryuta\| Yunoki, Naoko\| Hori, Shinichiro\| Kobayashi, Sayo\| Yamasaki, Yasushi\| Kawahara, Yoshiro\| Ishikawa, Hideki\| Okada, Hiroyuki\|
キーワード	anticoagulant agent bleeding endoscopic submucosal dissection gastric cancer heparin replacement warfarin
発行日	2020-11-01
出版物タイトル	Internal Medicine
巻	59巻
号	21号
出版者	The Japanese Society of Internal Medicine
開始ページ	2643
終了ページ	2651
ISSN	0918-2918
NCID	AA10827774
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2020 by The Japanese Society of Internal Medicine
論文のバージョン	publisher
PubMed ID	32641658
DOI	10.2169/internalmedicine.4998-20
Web of Science KeyUT	000589268900003
関連URL	isVersionOf https://doi.org/10.2169/internalmedicine.4998-20

Factors Predicting a Favorable Disease Course Without Anti-TNF Therapy in Crohn’s Disease Patients

JaLCDOI	10.18926/AMO/60363
フルテキストURL	74_4_265.pdf
著者	Inokuchi, Toshihiro\| Hiraoka, Sakiko\| Yasutomi, Eriko\| Oka, Shohei\| Yamasaki, Yasushi\| Kinugasa, Hideaki\| Takahar, Masahiro\| Kawano, Seiji\| Harada, Keita\| Okada, Hiroyuki\| Kato, Jun\|
抄録	Determining factors that predict a favorable disease course without anti-tumor necrosis factor (TNF) agents would help establish a more cost-effective strategy for Crohn’s disease (CD). A retrospective chart review was performed for CD patients with disease durations > 10 years who had not received anti-TNF agents as first-line therapy. Patients were divided into 2 groups: those who received neither anti-TNF agents nor bowel resection (G1), and those who had received an anti-TNF agent and/or bowel resection (G2). The patient backgrounds, therapies and clinical courses were compared between the groups. A total of 62 CD patients met the inclusion criteria (males: 71%; median duration of follow-up: 19 years). Six patients were included in G1; they were significantly less likely to have upper gastrointestinal lesions than G2 (p=0.007). A multivariate analysis revealed that the significant factors for avoidance of bowel resection without anti-TNF treatment were non-stricturing and non-penetrating behaviors, and absence of upper gastrointestinal lesions at the diagnosis (hazard ratios 0.41 and 0.52; p=0.004 and 0.04, respectively). In consideration of the long treatment course of CD, patients with non-stricturing and non-penetrating behaviors and no upper gastrointestinal lesions should not be treated with anti-TNF agents as first-line therapy.
キーワード	Crohn’s disease anti-TNF agent upper gastrointestinal lesion bamboo joint-like appearance
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2020-08
巻	74巻
号	4号
出版者	Okayama University Medical School
開始ページ	265
終了ページ	274
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2020 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	32843757
Web of Science KeyUT	000562508700001
NAID	120006880202

Fever and electrocoagulation syndrome after colorectal endoscopic submucosal dissection for patients with immunosuppressants and steroids

フルテキストURL	fulltext.pdf
著者	Yamamoto, Shumpei\| Kinugasa, Hideaki\| Yamasaki, Yasushi\| Hirai, Mami\| Ako, Soichiro\| Takei, Kensuke\| Igawa, Shoko\| Yasutomi, Eriko\| Oka, Shohei\| Ohmori, Masayasu\| Inokuchi, Toshihiro\| Harada, Keita\| Hiraoka, Sakiko\| Nouso, Kazuhiro\| Tanaka, Takehiro\| Okada, Hiroyuki\|
キーワード	colorectal ESD PECS electrocoagulation syndrome immunosuppressants and steroids post-ESD fever
発行日	2021-12-09
出版物タイトル	DEN Open
巻	2巻
号	1号
出版者	Wiley
開始ページ	e83
ISSN	2692-4609
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2021 The Authors.
論文のバージョン	publisher
PubMed ID	35310725
DOI	10.1002/deo2.83
Web of Science KeyUT	001047024900091
関連URL	isVersionOf https://doi.org/10.1002/deo2.83

Leucine-rich alpha-2 glycoprotein as a marker of mucosal healing in inflammatory bowel disease

フルテキストURL	fulltext.pdf
著者	Yasutomi, Eriko\| Inokuchi, Toshihiro\| Hiraoka, Sakiko\| Takei, Kensuke\| Igawa, Shoko\| Yamamoto, Shumpei\| Ohmori, Masayasu\| Oka, Shohei\| Yamasaki, Yasushi\| Kinugasa, Hideaki\| Takahara, Masahiro\| Harada, Keita\| Furukawa, Masaki\| Itoshima, Kouichi\| Okada, Ken\| Otsuka, Fumio\| Tanaka, Takehiro\| Mitsuhashi, Toshiharu\| Kato, Jun\| Okada, Hiroyuki\|
発行日	2021-05-27
出版物タイトル	Scientific Reports
巻	11巻
号	1号
出版者	Nature Research
開始ページ	11086
ISSN	2045-2322
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2021
論文のバージョン	publisher
PubMed ID	34045529
NAID	120007089817
DOI	10.1038/s41598-021-90441-x
Web of Science KeyUT	000658389400001
関連URL	isVersionOf https://doi.org/10.1038/s41598-021-90441-x

Liquid biopsy for patients with IBD-associated neoplasia

フルテキストURL	fulltext.pdf
著者	Kinugasa, Hideaki\| Hiraoka, Sakiko\| Nouso, Kazuhiro\| Yamamoto, Shumpei\| Hirai, Mami\| Terasawa, Hiroyuki\| Yasutomi, Eriko\| Oka, Shohei\| Ohmori, Masayasu\| Yamasaki, Yasushi\| Inokuchi, Toshihiro\| Takahara, Masahiro\| Harada, Keita\| Tanaka, Takehiro\| Okada, Hiroyuki\|
キーワード	IBD-associated neoplasia IBD-associated cancer Liquid biopsy ctDNA
発行日	2020-12-03
出版物タイトル	BMC Cancer
巻	20巻
号	1号
出版者	BMC
開始ページ	1188
ISSN	1471-2407
NCID	AA12034763
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s). 2020
論文のバージョン	publisher
PubMed ID	33272240
DOI	10.1186/s12885-020-07699-z
Web of Science KeyUT	000597268700004
関連URL	isVersionOf https://doi.org/10.1186/s12885-020-07699-z

Low Patient Weight and Long Intubation Time Are Key Factors for Pain during Colonoscopy

JaLCDOI	10.18926/AMO/65969
フルテキストURL	77_5_471.pdf
著者	Oka, Shohei\| Harada, Keita\| Yamamoto, Shumpei\| Yasutomi, Eriko\| Igawa, Shoko\| Ohmori, Masayasu\| Hirai, Mami\| Yamasaki, Yasushi\| Inokuchi, Toshihiro\| Kinugasa, Hideaki\| Takahara, Masahiro\| Hiraoka, Sakiko\| Okada, Hiroyuki\|
抄録	Although the clinical usefulness of colonoscopy has been established, the procedure remains painful for many patients. This study was designed to clarify the factors predicting colonoscopy-related pain. We evaluated 283 consecutive patients who completed a first-ever, total colonoscopy without sedatives or analgesics. The severity of pain symptoms was evaluated by a numeric rating scale (NRS) in a questionnaire immediately after the colonoscopy. Patient backgrounds and endoscopic findings were analyzed to evaluate their association with pain. Out of 283 patients, 53 scored their pain 0-1 on the NRS while 48 scored it 6-10. We defined the colonoscopies of the former and latter patients as painless and painful, respectively, and compared the two. Multivariate analyses revealed that low body weight (OR 4.95, 95%CI 1.89-12.99) and longer intubation time (OR 3.63, 95%CI 1.46-9.03) were significant risk factors for painful colonoscopy. To identify factors contributing to the increased intubation time, we divided subjects into short- and long-intubation-time groups based on a median insertion time of 7 min. Older age (OR 2.28, 95%CI 1.31-3.98), previous abdominal surgery (OR 1.93, 95%CI 1.13-3.32) and findings of invasive cancer (OR 10.90, 95%CI 1.34-88.90) were significant factors for longer intubation time.
キーワード	colonoscopy colonoscopy-related pain comfortable colonoscopy
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2023-10
巻	77巻
号	5号
出版者	Okayama University Medical School
開始ページ	471
終了ページ	478
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2023 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	37899258
Web of Science KeyUT	001108661600004

Modified line-assisted complete closure of the defect after gastric endoscopic full-thickness resection: a pilot study in porcine models

フルテキストURL	fulltext.pdf
著者	Yamasaki, Yasushi\| Ohmori, Masayasu\| Toyosawa, Junki\| Ako, Soichiro\| Okada, Hiroyuki\|
発行日	2022-05-13
出版物タイトル	Endoscopy International Open
巻	10巻
号	05号
出版者	Georg Thieme Verlag KG
開始ページ	E609
終了ページ	E615
ISSN	2364-3722
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2022. The Author(s).
論文のバージョン	publisher
PubMed ID	35571472
DOI	10.1055/a-1785-8589
Web of Science KeyUT	000794976400010
関連URL	isVersionOf https://doi.org/10.1055/a-1785-8589

Observer agreement for the diagnosis of intestinal acute graft‑vs.‑host disease based on the presence of villous atrophy in the terminal ileum

フルテキストURL	fulltext.pdf
著者	Sugihara, Yuusaku\| Hiraoka, Sakiko\| Yasutomi, Eriko\| Oka, Shohei\| Yamasaki, Yasushi\| Inokuchi, Toshihiro\| Kinugasa, Hideaki\| Takahara, Masahiro\| Morito, Yuki\| Takahashi, Sakuma\| Harada, Keita\| Tanaka, Takehiro\| Otsuka, Fumio\| Okada, Hiroyuki\|
キーワード	graft-vs.-host disease terminal ileum allo-hematopoietic stem cell transplantation villous atrophy endoscopy
発行日	2020-02-21
出版物タイトル	Experimental and Therapeutic Medicine
巻	19巻
号	4号
出版者	Spandidos Publications
開始ページ	3076
終了ページ	3080
ISSN	1792-0981
NCID	AA12610820
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© Sugiharaet al.
論文のバージョン	publisher
PubMed ID	32256795
DOI	10.3892/etm.2020.8538
Web of Science KeyUT	000523637100082
関連URL	isVersionOf https://doi.org/10.3892/etm.2020.8538

Prospective multicenter study of the efficacy and safety of cold forceps polypectomy for ≤ 6-mm non-ampullary duodenal low-grade adenomas

フルテキストURL	fulltext.pdf
著者	Kanzaki, Hiromitsu\| Horii, Joichiro\| Takenaka, Ryuta\| Nakagawa, Hiroyuki\| Matsueda, Kazuhiro\| Tsuzuki, Takao\| Kita, Masahide\| Yamasaki, Yasushi\| Tanaka, Takehiro\| Iwamuro, Masaya\| Kawano, Seiji\| Kawahara, Yoshiro\| Tomoda, Jun\| Okada, Hiroyuki\|
発行日	2022-06-10
出版物タイトル	Endoscopy International Open
巻	10巻
号	06号
出版者	Georg Thieme Verlag KG
開始ページ	E712
終了ページ	E718
ISSN	2364-3722
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2022. The Author(s).
論文のバージョン	publisher
PubMed ID	35859656
DOI	10.1055/a-1793-9439
Web of Science KeyUT	000826506700001
関連URL	isVersionOf https://doi.org/10.1055/a-1793-9439

Resection depth for small colorectal polyps comparing cold snare polypectomy, hot snare polypectomy and underwater endoscopic mucosal resection

フルテキストURL	fulltext.pdf
著者	Toyosawa, Junki\| Yamasaki, Yasushi\| Fujimoto, Tsuyoshi\| Tanaka, Shouichi\| Tanaka, Takehiro\| Mitsuhashi, Toshiharu\| Okada, Hiroyuki\|
発行日	2022-05-13
出版物タイトル	Endoscopy International Open
巻	10巻
号	05号
出版者	Georg Thieme Verlag KG
開始ページ	E602
終了ページ	E608
ISSN	2364-3722
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2022. The Author(s).
論文のバージョン	publisher
PubMed ID	35571476
DOI	10.1055/a-1785-8616
Web of Science KeyUT	000794976400009
関連URL	isVersionOf https://doi.org/10.1055/a-1785-8616

The Colon Wall Thickness Measured Using Transabdominal Ultrasonography Is Useful for Detecting Mucosal Inflammation in Ulcerative Colitis

フルテキストURL	fulltext.pdf
著者	Takahara, Masahiro\| Hiraoka, Sakiko\| Ohmori, Masayasu\| Takeuchi, Keiko\| Takei, Kensuke\| Yasutomi, Eriko\| Igawa, Shoko\| Yamamoto, Shumpei\| Yamasaki, Yasushi\| Inokuchi, Toshihiro\| Kinugasa, Hideaki\| Harada, Keita\| Ohnishi, Hideki\| Okada, Hiroyuki\|
キーワード	bowel wall thickness Mayo endoscopic subscore classification transabdominal ultrasonography ulcerative colitis
発行日	2022-09-15
出版物タイトル	Internal Medicine
巻	61巻
号	18号
出版者	The Japanese Society of Internal Medicine
開始ページ	2703
終了ページ	2709
ISSN	0918-2918
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2022 The Japanese Society of Internal Medicine
論文のバージョン	publisher
PubMed ID	35185047
DOI	10.2169/internalmedicine.8827-21
Web of Science KeyUT	000857218300001
関連URL	isVersionOf https://doi.org/10.2169/internalmedicine.8827-21

The Impact of KRAS Mutation in Patients With Sporadic Nonampullary Duodenal Epithelial Tumors

フルテキストURL	fulltext.pdf
著者	Kinugasa, Hideaki\| Kanzaki, Hiromitsu\| Tanaka, Takehiro\| Yamamoto, Shumpei\| Yamasaki, Yasushi\| Nouso, Kazuhiro\| Ichimura, Kouichi\| Nakagawa, Masahiro\| Mitsuhashi, Toshiharu\| Okada, Hiroyuki\|
発行日	2021-11
出版物タイトル	Clinical and Translational Gastroenterology
巻	12巻
号	11号
出版者	Lippincott Williams & Wilkins
開始ページ	e00424
ISSN	2155-384X
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2021 The Author(s).
論文のバージョン	publisher
PubMed ID	34797780
DOI	10.14309/ctg.0000000000000424
Web of Science KeyUT	000720492100001
関連URL	isVersionOf https://doi.org/10.14309/ctg.0000000000000424

Utility of Combined Use of Transabdominal Ultrasonography and Fecal Immunochemical Test Examinations in Ulcerative Colitis

JaLCDOI	10.18926/AMO/66674
フルテキストURL	78_1_079.pdf
著者	Takahara, Masahiro\| Hiraoka, Sakiko\| Ohmori, Masayasu\| Takeuchi, Keiko\| Takei, Kensuke\| Aoyama, Yuki\| Yasutomi, Eriko\| Igawa, Shoko\| Inokuchi, Toshihiro\| Toyosawa, Junki\| Yamasaki, Yasushi\| Kinugasa, Hideaki\| Harada, Keita\| Onishi, Hideki\| Okada, Hiroyuki\|
抄録	This study examined the utility of the combined use of transabdominal ultrasonography (TUS) and fecal immunochemical testing (FIT) to detect mucosal inflammation, vis-a-vis the Mayo endoscopic subscore (MES), in ulcerative colitis (UC). Sixty-three UC patients who underwent TUS and FIT were retrospectively enrolled. For TUS, the colon was divided into five segments, and the bowel wall thickness was measured and evaluated. The accuracy of FIT (> 100 ng/ml) in detecting mucosal inflammation (MES>0) was 0.93, whereas that of TUS (BWT>2 mm) in each segment was 0.84-0.97. The combined use of TUS and FIT may be helpful in noninvasive treatment strategies.
キーワード	transabdominal ultrasonography fecal immunochemical test ulcerative colitis Mayo endoscopic subscore
Amo Type	Short Communication
出版物タイトル	Acta Medica Okayama
発行日	2024-02
巻	78巻
号	1号
出版者	Okayama University Medical School
開始ページ	79
終了ページ	83
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2024 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	38419318

令和３年度岡山医学会賞　がん研究奨励賞（林原賞・山田賞）

タイトル（別表記）	The 2021 Incentive Award of the Okayama Medical Association in Cancer Research (2021 Hayashibara Prize and Yamada Prize)
著者	山崎泰史\|
出版物タイトル	岡山医学会雑誌
発行日	2023-04-01
巻	135巻
号	1号
開始ページ	9
終了ページ	11
ISSN	0030-1558
関連URL	isVersionOf https://doi.org/10.4044/joma.135.9
言語	日本語
著作権者	Copyright (c) 2023 岡山医学会
論文のバージョン	publisher
DOI	10.4044/joma.135.9

山崎 泰史