岡山大学温泉研究所
Acta Medica Okayama
0369-7142
56
1985
裏表紙
EN
Institute for Thermal Spring Research, Okayama University
No potential conflict of interest relevant to this article was reported.
岡山大学温泉研究所
Acta Medica Okayama
0369-7142
56
1985
奥付
EN
Institute for Thermal Spring Research, Okayama University
No potential conflict of interest relevant to this article was reported.
岡山大学温泉研究所
Acta Medica Okayama
0369-7142
56
1985
総目次
55
72
EN
Institute for Thermal Spring Research, Okayama University
No potential conflict of interest relevant to this article was reported.
岡山大学温泉研究所
Acta Medica Okayama
0369-7142
56
1985
終刊の辞
53
EN
No potential conflict of interest relevant to this article was reported.
岡山大学温泉研究所
Acta Medica Okayama
0369-7142
56
1985
胃悪性リンパ腫の内視鏡診断
45
52
EN
Hirofumi
Miyake
Hideo
Harada
Masatoshi
Yasuoka
Hiroo
Oka
Shuji
Matsumoto
Koji
Ochi
Masahiko
Takeda
Juntaro
Tanaka
Taisuke
Ohnoshi
Ikuro
Kimura
10.18926/21087
To delineate the pitfalls and counter-measures in the endoscopic diagnosis of gastric malignant lymphoma (GML), reviewed were 32 cases of primary GML and 16 cases of systemic ML with gastric involvement (secondary GML). 1) Accurate diagnosis of GML had been made in only 13 cases of primary GML ; 18 cases had been diagnosed of gastric cancer (GC); the remaining one of benign ulcer (BU). Review of the endoscopic films, however, revealed more than two of the three findings characteristic, but not pathognomomic, of GML in 84 percent. This result indicates that possibility of GML must be kept in mind in the differential diagnosis of malignant lesions despite its rarity, because endoscopists tend to be predisposed with an impression of GC. 2) Follow-up examinations made in nine cases of primary GML revealed marked changes in endoscopic findings in three cases : healing of an ulcer lesion in one case, healing of an ulcer lesion on an unchanged tumor in another and enlargement of a tumor in the remaining one. The first case had been followed up for two years with an impression of BU. This result indicates that improvement of ulcer does not necessarily rule out GML because it can show "malignant cycle" just as GC. 3) Endoscopic biopsy performed in 30 cases of primary GML had led to accurate diagnosis in only 16 cases and erroneous diagnosis of GC in five and no malignancy in nine. Review of the cases revealed the importance of having suspicion of GML at first from endoscopic findings, because it can lead to an increase of the number of biopsy specimens, careful selection of biopsy sites, careful use of biopsy instruments to obtain good specimens and closer contact with pathologists. 4) Prospective studies on systemic ML revealed gastric involvement in 17 percent. Examinations of the GI tract, especially of the stomach is one of the important steps for staging of systemic ML and deciding therapeutic modalities. 5) It is extremely difficult to diffierentate primary GML and secondary GML from endoscopic findings alone, although there are a few findings characteristic of the latter.
No potential conflict of interest relevant to this article was reported.
岡山大学温泉研究所
Acta Medica Okayama
0369-7142
56
1985
ラット血中代謝物質の日内変動に及ぼす温連浴の影響
35
43
EN
Toshinobu
Seno
Hideo
Harada
Masaaki
Mifune
Hiroshi
Morinaga
10.18926/21086
The effect of serial bathing (10-minute bathing in city water or Misasa hot spring, 40℃, once daily for one or four weeks) on the circadian variations of plasma metabolites was studied in three groups of rats : hot spring bathing rats, city water bathing rats and non-treated rats. Plasma obtained by decapitation at 8:00, 12:00, 16:00, 20:00 and 24:00 hours was analysed for catecholamines (CA), free fatty acids (FFA), cholesterol (C) and glucose. 1) Noradrenaline (NA) and adrenaline (A) were significantly lower at 24:00 hours with significantly lower 24-hour average concentrations and also with significantly different diurnal patterns in the 1-week hot spring bathing rats; in the 4-week hot spring bathing rats, lower 24-hour average concentrarion of A was the only significant finding. The results suggest the suppressive effect of hot spring bathing on the sympathetic system or pituitary gland-adrenal medulla; they also suggest the adaptation to hot spring bathing. 2) Free fatty acids were significantly higher in the 1-week hot spring bathing rats at 12:00 hours as compared with non-treated rats and city water bathing rats. The 4-week hot spring bathing rats showed concentration of FFA not different from the remaining two groups of rats. No significant difference was noted in diurnal patterns among the three groups of rats. The results suggest that the high FFA concentrations in the 1-week hot spring bathing rats are related to the physico-chemical constituents of the hot spring to some extent and that the rats adapt
themselves to bathing during the 4-week preriod. 3) Cholesterol was significantly lower in the 4-week hot spring bathing rats as compared with non-treated rats and city water bathing rats; no different diurnal patterns were noted among the three groups of rats. The results suggest the suppressive effect of 4-week hot spring bathing on plasma cholesterol concentrations as reported previously by us. 4) No Significant difference was noted in concentrations as well as in diurnal patterns of plasma glucose among the three groups of rats. The results suggest that bathing has no significan effect on concentrations and diurnal patterns of plasma glucose in healthy rats.
No potential conflict of interest relevant to this article was reported.
岡山大学温泉研究所
Acta Medica Okayama
0369-7142
56
1985
水試料の敢素同位体比の自動測定
27
34
EN
Hitoshi
Chiba
Hitoshi
Sakai
Masatoshi
Yasutake
10.18926/21085
The automatic sample preparation system for oxygen isotope analysis of natural water samples was constructed. The system is essentially a modification of that originally designed by W. Dansgaard in the University of Copenhagen. Sixty water samples of 5 ml each are automatically equilibrated with CO(2) of 30 ml NTP each within 4.5 hours. The equilibrated CO(2) gases are successively measured for their oxygen isotopic ratios by an automatic mas-sspectrometer, VG903. The time required for the
measurement of the 60 CO(2) samples is about 15 hours; thus approximately 20 hours are required to complete the isotopic measurements of 60 water samples. The accuracy of the oxygen isotopic analyses is about 0.1%. The result of oxygen isotopic analyses by the automatic preparation system agrees with that of the conventional method within about +0.1%. The results indicate that the automatic preparation system is applicable for the oxygen isotope analysis of natural water samples.
No potential conflict of interest relevant to this article was reported.
岡山大学温泉研究所
Acta Medica Okayama
0369-7142
56
1985
慢性閉塞性肺疾患の温泉療法(3年間の入院症例の検討)
23
26
EN
Michiyasu
Sudo
Haruki
Komagoe
Yoshiro
Tanizaki
Hiroshi
Morinaga
10.18926/21084
During last three years, 41 patients with chronic obstructive lung disease (39 cases with bronchial asthma and 2 cases with chronic bronchiolitis) received spa therapy at Department of Medicine, Okayama University Medical School, Misasa Medical Branch. 1. Twenty three (56%) out of 41 cases came from Okayama prefecture and 10 cases (24.4%) from Tottori prefecture for spa therapy. In
twenty five (61.0%) out of 41 cases, their ages were over 50 years. 2. Thirty nine patients with bronchial asthma were divided into three asthma types classified by clinical symptoms : Ia ; 16 cases (41.0%), Ib; 13 cases (33.3%) and II ; 10 cases (25.7%). Pulmonary function tests for these patients showed that small airways obstruction was most remarkable in type II asthma. 3. The mean serum IgE level of all asthmatic patients (39 cases) was 653.9U/ml. In skin test by allergens, positive immediate skin reaction was shown in 18 cases (46.2%) by Candida and 12 cases (30.8%) by house dust. Specific IgE anti-bodies were found in 9 cases (23.1%) for house dust and 3 cases (7.7%) for Candida.
No potential conflict of interest relevant to this article was reported.
岡山大学温泉研究所
Acta Medica Okayama
0369-7142
56
1985
Studies on the release of histamine from basophils 5. Clinical evaluation
17
21
EN
Yoshiro
Tanizaki
Haruki
Komagoe
Michiyasu
Sudo
Hiroshi
Morinaga
10.18926/21083
過去3年間にわたり,気管支喘息患者末梢血好塩基球からのヒスタミン遊離について,ヒスタミン自動分析装置を用いて全血法により検討を加えてきた. 1. 抗ヒトIgE によるヒスタミン遊離は,症例間で著しい差がみられた. この際血清IgE値が高値を示す症例では全般的に高度なヒスタシソ遊離がみられたが,血清IgE値が正常かまたはむしろ低値を示す症例のヒスタミン遊離は,かなり高度なものから全くみられないものまでさまざまであった. 2.ハウスダストやカンジダなどの抗原物質によるヒスタミン遊離は,特異的IgE抗体依存性であり,抗体価が上昇するにつれヒスタミン遊離は高度となる傾向がみられた. しかし,ハウスダストとカンジダによるヒスタミン遊離には若干の差がみられた. すなわち,ハウスダストと抗ヒトIgE によるヒスタミン遊離の間には密接な関連がみられたが,カンジダと抗ヒトIgEの間には全く関連がみられなかった. またカンジダによるヒスタミン遊離においては,IgE系反応以外の反応が関与する可能性が一部示唆された.
No potential conflict of interest relevant to this article was reported.
岡山大学温泉研究所
Acta Medica Okayama
0369-7142
56
1985
人工的強食塩泉の組織循環におよぽす影響
13
16
EN
Yoshiaki
Komoto
Tomoji
Kohmoto
Mitsuru
Sunakawa
Junko
Komoto
10.18926/21082
Changes in partial pressures of each tissue gas and tissue perfusion were evaluated in the 2.5% artificial salt baths by means of medical mass spectrometry using 9 rabbits. The level of subcutaueous PO(2) lowered by 18% and PCO(2) elevated by 7 % compared with the plain water bath. The tissue perfusion volume was found increased by few %. It is assumed that we owe the warm feeling after taking concentrated salt baths to the improved tissue perfusion.
No potential conflict of interest relevant to this article was reported.
岡山大学温泉研究所
Acta Medica Okayama
0369-7142
56
1985
夜尿症に対する人工炭酸泉浴の試み
9
11
EN
Junko
Komoto
Yoshiaki
Komoto
10.18926/21081
The artificial CO(2) bath was prescribed for two enuretic boys with bladder-sensitive or parasympaticotonic type. A tablet of 50 g, made from sodium bicarbonate and succinic acid, was put in a bath-tub of 150-200 L at 40℃. Each patient was recommended to take a bath with his mother longer than ten minutes, and to mark the presence or the absence of enuresis every day. Outcome results of case 1 on CO(2) bath is shown in tabel 1 and results of case 2 on CO(2) bath is shown in table 3. Both two cases became free from enuresis 7-10 days after the initiation of the artificial CO(2) bathing. Etiological mechanisms of enuresis seem to be multi-factorious, with underlining networks of central- and autonomous nerve systems for the control of sleep and bladder. It is suspected that some improvement of peripheral circulation by CO(2)-bathing leading to keep the body warm may be one of the contributing factors which prolong the intervals of urination, resulting in autonomous normalization, at least, for the cases of bladder-sensitive enuresis, Further case studies are needed to support this assumption.
No potential conflict of interest relevant to this article was reported.
岡山大学温泉研究所
Acta Medica Okayama
0369-7142
56
1985
興味ある心因性発熱の1症例
5
8
EN
Junko
Komoto
Ikuko
Yasumoto
10.18926/21080
An 18 years old girl, who developed high fever following sore throat without demonstrable organic findings, was diagnosed as having psychogenic fever. Symptom was apparently related to her psychological conflicts in an unconscious pursuit of both the primary gain (avoidance to take examination for college) and the secondary gain (satisfaction for dependancy-need). Initiation, exacerbation and termination of fever were not under voluntary control but produced by self-induced hypnosis. Details of her hypnotic process together with her insight into the condition after psychotherapy were described as clinical data.
No potential conflict of interest relevant to this article was reported.
岡山大学温泉研究所
Acta Medica Okayama
0369-7142
56
1985
三朝温泉地の自然放射能と住民の末梢血染色体異常について
1
4
EN
Hiroshi
Morinaga
Masaaki
Mifune
Katsuaki
Furuno
10.18926/21079
Misasa Spa is one of the most highly radioactive hot springs in Japan, the waters of which contain mainly (222)Rn (437±132 Bq/liter). Radon contents of indoor air of private houses and health resort hotels (built of wood) at Misasa Spa range from 18.5 to 55.5 mBq/liter and 22.2 to
129.5 mBq/liter, respectively. Radon contents in the air of facilities using spring waters at Misasa Branch Hospital of Okayama University were measured to be ; bathroom 807±78 mBq/liter; Hubbardtank bathroom 5306±2568 mBq/liter ; the drinking hall 1491±178 mBq/liter. The environmental and dose rate inside private houses has been measured to be 14.0±1.8 μR/h. Chromosome aberrations (dicentrics) in the peripheral blood lymphocytes of residents of Misasa Spa were investigated in 14 persons; the mean value of aberration frequencies were 0.21%.
No potential conflict of interest relevant to this article was reported.
岡山大学温泉研究所
Acta Medica Okayama
0369-7142
56
1985
目次
EN
Institute for Thermal Spring Research, Okayama University
No potential conflict of interest relevant to this article was reported.
岡山大学温泉研究所
Acta Medica Okayama
0369-7142
56
1985
表紙
EN
Institute for Thermal Spring Research, Okayama University
No potential conflict of interest relevant to this article was reported.