JaLCDOI 10.18926/40076
タイトル(別表記) The involvement of ear and throat in rheumatoid arthritis II. On the Rheumatoid Arthritis of Cricoaryenoid Joint
著者 小田 昤|
抄録 Until 1955 a few reports had been made concerning this problem. On December 1955. Montgomery, Perone and Schall reported four cases of rheumatoid arthritis of cricoarytenoid joint. It seemed to have interested other authors so that Saunders, Pearson, BakerBywaters, Copeman and Polisar reported their clinical findings. In 1957 Pearson presented a histological section of cricoarytenoid joint, showing villous synovial proliferation. In 1959 Montgomery reported another series of additional cases and microscopical findings of the cricoarytenoid joint of two patients with rheumatoid arthritis. This study did not show a complete fibrous ankylosis but severe arthritic changes were seen. In the same year Copeman et al. reported an autopsy case of rheumatoid arthritis with ankylosis of cricoarytenoid joint. In early 1960's Grossman et al. examined 55 patients with rheumatoid arthritis and found 18 patients with some suggestive evidence of cricoarytenoid arthritis. Lofgren and Montgomery examined 100 patients of rheumatoid arthritis, finding 26% of them had involvement of cricoarytenoid joint. They stated that this disease seemed to be more common and more severe in female. Bienenstock stated 17 cases of 64 randomly selected patients with rheumatoid arthritis had one or more symptoms considered to be characteristic of cricoarytenoid arthritis. He claimed that arthritis of cricoarytenoid joint occured much more frequently in patients with rheumatoid arthritis than had been suspected. At postmortem examination Grossman saw histological changes of cricoarytenoid joint characteristics of rheumatoid arthritis in 5 of 11 autopsied patients with rheumatoid arthritis and Bienenstock found the same in 7 of 8 patients. In 1963 for the third time Montgomery discussed of cricoarytenoid arthritis, based on his own experiences and many available literatures. Pathologic changes range between the mere synovial thickning and the complete disruption. Montgomery believed as others did, that in ankylosing chronic stage inspiratory bowing of both vocal cords and absolute fixation of arytenoid cartilage were diagnostic signs of rheumatoid arthritis of cricoarytenoid joint. In 1958 Darke, Wolman and Young reported five cases of laryngeal stridor, where in four cases tracheotomy became necessary. Two of them were brought to autopsy and histological examination. They found evidence of the nerve degeneration and mobile cricoarytenoid joint. The cause of nerve degeneration in the second case was an ischaemic neuropathy from rheumatoid arteritis of vasa nervorum. These findings were different from those of Montgomery and others. In 1965 Wolman, Darke and Young had an opportunity of six more autopsy examples. They confirmed from their own pathologic findings that laryngeal stridor occuring in rheumatoid arthritis was due mainly to arteritis of the vasa nervorum causing ischaemic neuropathy and that polymyositis and joint disease might augment this effect. Woldorf and Webb et aI. introduced both of these opinions. Anyhow, in U. S. A. and in England 25%-28% of rheumatoid arthritis seems to have rheumatoid arthritis of cricoarytenoid joint. On the other hand in our country there has been seen no report on rheumatoid arthritis of cricoarytenoid joint. In order, therefore, to investigate this problem author examined in medical clinic of Misasa branch hospital of Okayama university school of medicine 76 patients of classical and definite rheumatoid arthritis. Their complaints were as follows. 1) dryfeeling of throat 17 (22.4%) 2) slight hoarseness 11 (14.5%) 3) choking by long conversation 1 (1.32%) 4) slight dysphagia 2 (2.6%) The larynx was mirrored indirectly by Türk's, Killian's and Avellis's position. Any redness, swelling of mucous membrane, abnormality of vocal cords and arytenoid cartilage were not found.
出版物タイトル 岡山大学温泉研究所報告
発行日 1978-03-25
47巻
開始ページ 25
終了ページ 32
ISSN 0369-7142
言語 Japanese
論文のバージョン publisher
NAID 40000321117
著者 岡山大学温泉研究所|
発行日 1978-03-25
出版物タイトル 岡山大学温泉研究所報告
47巻
資料タイプ その他
著者 岡山大学温泉研究所|
発行日 1978-03-25
出版物タイトル 岡山大学温泉研究所報告
47巻
資料タイプ その他
JaLCDOI 10.18926/21195
タイトル(別表記) The treatment of rheumatoid arthritis with D-penicillamine. Preliminary report
フルテキストURL pitsr_047_069_075.pdf
著者 石井 廣文| 高杉 潔| 北山 稔| 森永 寛|
抄録 Twenty patients with classical or definite rheumatoid arthritis were treated with D-Penicillamine. Favorable responses were observed in 75% of the patients. Significant improvement in clinical parameters, such as ESR, CRP, titers of rheumatoid factor and so forth, was noticed in twenty weeks of treatment. Withdrawal from penicillamine treatment was necessitated in four patients because of adverse reactions to the drug. Untoward effects included skin rash (most frequent), pruritis and loss of taste. From this preliminary study we presume that in earlier cases in which rheumatoid lesions may be reversible, more favorable clinical effects would be expected from this agent.
出版物タイトル 岡山大学温泉研究所報告
発行日 1978-03-25
47巻
開始ページ 69
終了ページ 75
ISSN 0369-7142
言語 Japanese
論文のバージョン publisher
NAID 120002310960
JaLCDOI 10.18926/21194
タイトル(別表記) Stable isotope study of the hotsprings and volcanoes of Hokkaido, Japan
フルテキストURL pitsr_047_055_067.pdf
著者 松葉谷 治| 酒井 均| 上田 晃| 堤 真| 日下部 実| 佐々木 昭|
抄録 Stable isotope ratios of hydrogen, oxygen, carbon and sulfur of precipitation, thermal and mineral waters, and volcanic gases were measured. The isotopic data combined with chemical and geological information were discussed in terms of origin and evolution of the hotsprings and volcanic gases. The hotsprings along the Uchiura Bay, Oshima Peninsula are mostly near-neutral NaCl-type thermal water and may be divided into three groups : (1) thermal waters isotopically similar to the precipitation of this area, (2) those similar in D/H to the local meteoric waters but enriched by 2 to 3‰ in (18)O compared to the latter, and (3) those enriched significantly in both D and (18)O relative to the local meteoric waters. The first and second types of thermal water probably form from local meteoric water which percolates through "Green Tuff" formations and acquires dissolved chemicals from them. However, high salt concentration and the oxygen isotope shift (thesecond type) may imply that the NaCl-type water of volcanic origin might be involved. On the other hand, the waters of the third group can be explained by mixing of modern sea water into the second type thermal water (in case of Yachigashira) or by incorporation of fossil sea water of Tertiary origin into modern meteoric water (Nigorigawa). Except for Esan, Noboribetsu and Atosanupuri volcanic systems, waters from all the hotsprings and volcanic fumaroles associated with Quaternary volcanic rocks are meteoric in origin. Thermal waters at Esan, Noboribetsu and Atosanupuri have δD = -30~-50 and δ(18)O = -1~+ 3‰ and are enriched in D and (18)O relative to local meteoric water of the respective area. The origin of these waters and the mechanism (s) controlling the isotope ratios could not be made clear by the present study. Interesting is the finding that at Esan, Noboribetsu and Atosanupuri, thermal waters are enriched in D and (18)O relative to near-by fumarolic gases. The enrichment factor is 18 to 26‰ for hydrogen and 4 to 6‰ for oxygen, implying that more than one stages of liquidvapor separation are taking place in underground hydrothermal systems.
出版物タイトル 岡山大学温泉研究所報告
発行日 1978-03-25
47巻
開始ページ 55
終了ページ 67
ISSN 0369-7142
言語 Japanese
論文のバージョン publisher
NAID 40000321119
JaLCDOI 10.18926/21193
タイトル(別表記) Some improvements in making of polished thin section
フルテキストURL pitsr_047_049_054.pdf
著者 麻田 斉|
抄録 Making of polished thin section is improved by application of overturn pasting and grinding by rounding wet emery cloth.
出版物タイトル 岡山大学温泉研究所報告
発行日 1978-03-25
47巻
開始ページ 49
終了ページ 54
ISSN 0369-7142
言語 Japanese
論文のバージョン publisher
NAID 120002311008
JaLCDOI 10.18926/21192
タイトル(別表記) Enumeration of T-cells in peripheral blood as well as in joint fluid from patients with rheumatoid arthritis (RA) and the effect of cyclophosphamide
フルテキストURL pitsr_047_041_048.pdf
著者 時岡 正明| 高杉 潔|
抄録 Gradient centrifugation was quite useful in obtaining "mononuclear" cell fractions from synovial fluids derived from patients with rheumatoid arthritis. The ratio of lymphocytes to monocytoid cells was similar to that seen in peripheral blood. Prior treatment of the fluid with hyaluronidase was found to be necessary to obtain a satisfactory yield of the cells. Sheep erythrocyte rosette-forming lymphocytes (T-cells) were studied in 18 paired samples of synovial fluid and blood in RA and 15 control blood samples from normal persons were also examined. In the paired synovial fluid and blood samples from the RA patients, the mean percentages of the T-cells were 56.6 and 47.1 respectively and the difference was statistically significant (0.01<p<0.05). There was no significant difference between T-cell percentages in rheumatoid and control peripheral blood. In two RA patients receiving cyclophosphamide over an average period of 20 weeks, sequential studies of T-cells were performed on both the blood and synovial fluid. By the tenth week of treatment, they were markedly reduced in both synovial fluid and peripheral blood. By the 12th to the 15th week, however, at a time when the cumulative dose of cyclophosphamide was 5,000 mg, a rebound increase in T-cells was observed in the synovial effusion. The numbers of the T-cells in the blood concomitantly showed only a minimal rebound.
出版物タイトル 岡山大学温泉研究所報告
発行日 1978-03-25
47巻
開始ページ 41
終了ページ 48
ISSN 0369-7142
言語 Japanese
論文のバージョン publisher
NAID 120002310963
JaLCDOI 10.18926/21191
タイトル(別表記) Petrological study of the Okutsu granodioritic mass in the northern part of Okayama Prefecture. Japan - Part 1 Geology and petrography
フルテキストURL pitsr_047_033_040.pdf
著者 先山 徹|
抄録 The Late Mesozoic granitic rocks have been studied in the Okutsu area, northern Okayama Prefecture. Main portion of the area is occupied by the Okutsu granodioritic mass. It consists of mediumgrained hornblende-biotite granodiorite, mediumgrained biotite granite, fine-grained biotite granite, and aplitic granite in the succeeding order of intrusion. Contacts between these rock-types are generally gradational and An-contents of both core and margin of the plagioclase progressively decrease with increasing acidity of the rocks. These facts indicate a cognate origin of various rock-types of this mass. The Kamisaibara granite, rather uniform coarse-grained hornblende-biotite granite, occurs in large batholith. It is inferred petrographically that the Kamisaibara granite is a member of the Ningy6,t6ge granite widely distributed on the north of this area. Field evidence suggests that the Ningyo-toge granite was intruded by the Okutsu granodioritic mass.
出版物タイトル 岡山大学温泉研究所報告
発行日 1978-03-25
47巻
開始ページ 33
終了ページ 40
ISSN 0369-7142
言語 Japanese
論文のバージョン publisher
NAID 120002310948
JaLCDOI 10.18926/21189
タイトル(別表記) The involvement of ear and throat in rheumatoid arthritis I. Hearing in patients with rheumatoid arthritis
著者 小田 昤|
抄録 Since Copeman's report on patients with hearing impairment as "rheumatoid otoarthritis?" has introduced, there have been a few reports on hearing impairment in patients with rheumatoid arthritis such as Goodwill et al. and Djupesland et aI. in European countries. On the contrary in our country there is no reference in association with hearing impairment of rheumatoid arthritis in rheumatic or otological literatures. An audiometric survey was carried out in 76 patients admitted in the Misasa branch hospital of Okayama university school of medicine on the classical or definite rheumatoid arthritis. Patients were excluded from the series if they had scarred or perforated tympanic membrane and history of otorrhea. Thus 67 patients have come to study. As control group, 15 healthy persons in hearing for each ten years, 15-24, 25-34, 35-44, 45-54, 55-64, and over 60 years, were selected and as a physiological hearing limit, rejection limit of hearingloss in dB. was made. Among 67 patients, 111 ears had hearingloss within the above mentioned rejection limit. In 23 ears, hearingloss in dB. were partial or as a whole out of the limit. They have all air-bone-conduction gap. After inflation of Eustachien tube, in most of them air conduction ability showed nearly the same level of bone conduction. In three cases even by inflation, airconduction level did not move. In one case the left side had effusion liquid and its RAreaction was positive. TwO of the former patients and the one whose effusion liquid had positive RA-test followed up for about 3 years. In the former two cases, hearing impairment got worse little by little and recovery by inflation was not seen. On both cases Gelle's test was positive. In the latter hearing impairment slowly got worse. This had lasted for about two months and had recoverd. In the se four cases heairng impairment was probably related to the rheumatoid arthritis and no other causes could be found.
出版物タイトル 岡山大学温泉研究所報告
発行日 1978-03-25
47巻
開始ページ 5
終了ページ 24
ISSN 0369-7142
言語 Japanese
論文のバージョン publisher
NAID 120002311022
JaLCDOI 10.18926/21188
タイトル(別表記) A useful procedure for taking photograph of resected specimens
フルテキストURL pitsr_047_001_003.pdf
著者 野一色 泰晴|
抄録 Histochemical, biochemical, and electron microscopic investigations on resected specimen have expanded in almost exponential manner in the past ten years and taking photograph of the specimens is also of importance for the examination of them. The specimens are, however, damaged during the time of taking photograph by various factors such as heat, dryness, light etc. For the investigations of this kind, the most important requirement for preservation of protoplasmic structure is to interrupt the dynamic process of the cell as prompt as possible and to stabilize the structure with a minimum of change. To prevent the damage of the specimens during the time of taking photograph, the following procedure is proposed: The specimen is dipped into cold saline solution, phosphate buffer, or cacodylate buffer. as soon as possible after operation. Photographic procedure is carried out upon the specimen dipped into the solution. By this procedure, the specimens can be protected from being damaged by heating and drying. Furthermore, the specimen can be preserved in its original shape due to the aid of buoyancy. This procedure has an another advantage : The photograph is in principle free from halation on the surface of the specimens. Thus, the proposed procedure is very useful for taking photograph of resected specimens in general.
出版物タイトル 岡山大学温泉研究所報告
発行日 1978-03-25
47巻
開始ページ 1
終了ページ 3
ISSN 0369-7142
言語 Japanese
論文のバージョン publisher
NAID 120002311000
著者 岡山大学温泉研究所|
発行日 1978-03-25
出版物タイトル 岡山大学温泉研究所報告
47巻
資料タイプ その他
著者 岡山大学温泉研究所|
発行日 1978-03-25
出版物タイトル 岡山大学温泉研究所報告
47巻
資料タイプ その他