start-ver=1.4
cd-journal=joma
no-vol=46
cd-vols=
no-issue=
article-no=
start-page=45
end-page=59
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1977
dt-pub=19770325
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=A FORTRAN data processing system for the epidemiological data on rheumatic diseases - Part 1. Basic programs for deposit and retrieval of data
kn-title=FORTRAN を用いたリウマチ性疾患の疫学調査データ処理の試み 第1報 コンピューター用エンコード法とそのInput･Outputの方法について
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=A set of FORTRAN programs for small computer is described for deposit and retrieval of the epidemiological data, which have been compiled
at the Kami-hojo-cho district in Feb. 1972and
Feb. 1975. A data file is constructed on a magnetic disk. The following items are recorded and registered on the disk for every person: identification number, full name in Japanese alphabet, sex, date of birth, weight, height, blood pressures, chemical characterics of blood serum and urine, and various complaints of clinical significance (fever, morning stiffness, arthralgia, joint swelling, myalgia, cutaneous rash, aphthous stomatitis, dry eyes, dry mouth, joint deformity, subcutaneous nodules, lymph and parotid gland enlargement, struma, heart murmur, and neulogical findings). All information per one person requires only two IBM cards due to compact encoding of original records. The encode-decode procedures are explained also in the text.
en-copyright=
kn-copyright=

en-aut-name=ItohKeiko
en-aut-sei=Itoh
en-aut-mei=Keiko
kn-aut-name=伊東恵子
kn-aut-sei=伊東
kn-aut-mei=恵子
aut-affil-num=1
ORCID=

en-aut-name=KitayamaMinoru
en-aut-sei=Kitayama
en-aut-mei=Minoru
kn-aut-name=北山稔
kn-aut-sei=北山
kn-aut-mei=稔
aut-affil-num=2
ORCID=

en-aut-name=MorinagaHiroshi
en-aut-sei=Morinaga
en-aut-mei=Hiroshi
kn-aut-name=森永寛
kn-aut-sei=森永
kn-aut-mei=寛
aut-affil-num=3
ORCID=

en-aut-name=MatsuiYoshito
en-aut-sei=Matsui
en-aut-mei=Yoshito
kn-aut-name=松井義人
kn-aut-sei=松井
kn-aut-mei=義人
aut-affil-num=4
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学温泉研究所温泉医学部門

affil-num=2
en-affil=
kn-affil=岡山大学温泉研究所温泉医学部門

affil-num=3
en-affil=
kn-affil=岡山大学温泉研究所温泉医学部門

affil-num=4
en-affil=
kn-affil=岡山大学温泉研究所地殻熱学部門
END

start-ver=1.4
cd-journal=joma
no-vol=46
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1977
dt-pub=19770325
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=裏表紙
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=Institute for Thermal Spring Research, Okayama University
en-aut-sei=Institute for Thermal Spring Research, Okayama University
en-aut-mei=
kn-aut-name=岡山大学温泉研究所
kn-aut-sei=岡山大学温泉研究所
kn-aut-mei=
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=
END

start-ver=1.4
cd-journal=joma
no-vol=46
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1977
dt-pub=19770325
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=奥付
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=Institute for Thermal Spring Research, Okayama University
en-aut-sei=Institute for Thermal Spring Research, Okayama University
en-aut-mei=
kn-aut-name=岡山大学温泉研究所
kn-aut-sei=岡山大学温泉研究所
kn-aut-mei=
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=
END

start-ver=1.4
cd-journal=joma
no-vol=46
cd-vols=
no-issue=
article-no=
start-page=61
end-page=70
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1977
dt-pub=19770325
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Study of metabolism of uric acid. (1) Observation of uric acid values
kn-title=尿酸代謝に関する研究 （1）尿酸値に関する2･3の観察
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Uric acid was measured in serum and urine of the ambulant and hospitalized patients with various disorders including gout. in Misasa-Branch Hospital of Okayama University Medical School from January 1975 to December 1976. Serum and urine samples were obtained from 283 males and 260 females, and from 2 males respectively. The results are as follws; (1) Uric acid in males was 1.4 mg/100mf higher than in females. (2) Uric acid in males decreased with ages, showing two peaks between 15 and19 , and between 35 and 44 years old. (3) Uric acid in females showed low levels between third and fifth decades and increased thereafter with ages. (4) There were many fatty subjects among the patients with gout. (5) An increase in total daily excretion of urinary uric acid was observed concomitantly with increased daily urine volume. (6) Periodical fluctuations of uric acid in serum and other clinical findings were show in several cases of gout, who had been controlled in MisasaBranch Hospital for several years.
en-copyright=
kn-copyright=

en-aut-name=AokiHiroko
en-aut-sei=Aoki
en-aut-mei=Hiroko
kn-aut-name=青木宏子
kn-aut-sei=青木
kn-aut-mei=宏子
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院内科
END

start-ver=1.4
cd-journal=joma
no-vol=46
cd-vols=
no-issue=
article-no=
start-page=37
end-page=43
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1977
dt-pub=19770325
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Determination of manganese in serum by atomic absorption spectrophotometry
kn-title=原子吸光分光分析法による血清マンガンの測定について
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=The manganese (Mn) concentrations in serum of 40 healthy controls (9 males and 31 females), and of 26 patients with rheumatoid arthritis (4males and 22 females) were determined using a HITACHI MODEL 207 atomic absorption spectrophotometer. Wavelength of Mn determination was setted at 2795 A. Flow rate of acetylene was setted at 3.0 l/min and lamp current was setted at 10 rnA. The serum samples were ashed by IPC MODEL 1003plasma machine, and dissolved in 3N-HCl and evapolate on the hot plate, and redissolved in constant volume of 0.1 N-HCl. These sample solution were aspirated directly into the burner. Mn levels in serum were estimated by standard curve. The mean recoverry rate of ashedsample solution was 100.1%, and that of serum by ashing process was 101.6%. The serum Mn levels in 40 healthy controls and 26 patients with rheumatoid arthritis were 2.19 ± 0.34 (S.D.), 3.04 ± 1.01 (S.D.) μg/100ml respectively. The serum Mn levels in rheumatoid arthritis were significantly higher than healthy control levels (p<0.001). In 10 of 26 cases (38%) with rheumatoid arthritis, the serum Mn levels were shown to be above the upper limit of 5% rejection limit of healthy controls.
en-copyright=
kn-copyright=

en-aut-name=FurunoKatsushi
en-aut-sei=Furuno
en-aut-mei=Katsushi
kn-aut-name=古野勝志
kn-aut-sei=古野
kn-aut-mei=勝志
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学温泉研究所温泉医学部門
END

start-ver=1.4
cd-journal=joma
no-vol=46
cd-vols=
no-issue=
article-no=
start-page=25
end-page=35
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1977
dt-pub=19770325
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Determination of copper and zinc in serum by atomic absorption spectrophotometry
kn-title=原子吸光分光分析法による血清銅･亜鉛の同時測定について
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Copper (Cu) and Zinc (Zn) in serum of 113 healthy controls (43 males and 70 females) and of 68 patients with rheumatoid arthritis (19 males and 49 females) were determined using a HITACHI MODEL 207 atomic absorption spectrophotometer. Wavelength and lamps current of Cu and Zn were setted at 3247 A, 2139 A, and 10mA, 9mA respectively. Flow rate of acetylene and air were setted at 3.0 l/min, and 13.0 l/min. The stock standard solutions of Cu and Zn were 0.5 mg, 1.0mg, 2.0mg and 3.0mg per 100mE in 0.01 N·HCl. For working standard solutions, these stock standard solutions were diluted to 50μg/100ml. 100μg/100ml, 200μg/100ml and 300μg/100ml with 20% glycerine. Serum and working standard so· lutions of Cu and Zn were diluted five fold with deionized distillation water, then aspirated directly into the burner. The relative absorbance was expressed as scale reading by a HITACHI MODEL QPD-54 recorder. Various acids and other elements had few influences on the determi· nations of Cu and Zn. The mean recovery rate of Cu and Zn in serum were 100.5% and 100.8% respectively. By this method, the levels of Cu and Zn in healthy controls were 103.0±14.5 (S.D.), 116.2±18.6 (S.D.) μg/100ml in males and 108.7±19.6 (S. D.), 110.3±14.7 (S.D.) μg/100ml in females respectively. No sex difference were observed. The ratio of Cu and Zn (Cu/Zn ratio) of healthy controls were 0.89±0.17 (S. D.) in males and O.99±0.25 in (S.D.) females. The sex differrences of Cu/Zn ratio were statistically significant (p<0.05). The levels of Cu and Zn in rheumatoid arthritis were 141.7±25.2 (S.D.). 89.1±14.5 (S.D.) /-Lg/100 mP and 154.l±29.7 (S.D.), 86.7±18.1 (S.D.) μg/100ml in females respectively. No sex differren· ces were observed. The Cu/Zn ratio were 1.64±0.43 (S.D.) in males and 1.82±0.48 (S.D.) in females, wich showed no sex differrences. In patients with rheumatoid arthritis, serum Cu levels were significantly higher (P<0.001) and serum Zn levels were significantly lower (P<0.001) than in healthy controls in both sexes. The Cu/Zn ratio were significantly higher (P<0.001) rheumatoid arthritis than in controls. The serum Cu in 13 of 19 males (68%), and 30 of 49 females (61 %), with rheumatoid arthritis were shown to be above the upper limit of 5% rejection limit in healthy controls. The serum Zn in 3 of 19 males (16%), and in 24 of 49 (47%) with rheumatoid arthritis were shown to be below the lower limit 5% rejection limit in healthy controIs. The Cu/Zn ratio in rheumatoid arthritis, in 14 of 19 males (74%), and in 35 of 49 females (71%) were shown to be above the upper limit of 5% rejection limit in healthy of males and females. So, differences in Cu/Zn ratio between healthy controls and rheumatoid arthritis were proved to be more pronounced.
en-copyright=
kn-copyright=

en-aut-name=FurunoKatsushi
en-aut-sei=Furuno
en-aut-mei=Katsushi
kn-aut-name=古野勝志
kn-aut-sei=古野
kn-aut-mei=勝志
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学温泉研究所温泉医学部門
END

start-ver=1.4
cd-journal=joma
no-vol=46
cd-vols=
no-issue=
article-no=
start-page=15
end-page=23
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1977
dt-pub=19770325
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Circulatory changes in rheumatoid fingers as estimated by thermography and photoelectric plethysmography
kn-title=サーモグラフィーおよび指尖容積脈波による慢性関節リウマチ患者手指の循環障害の検討
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=In an attempt to evaluate circulatory changes in patients with rheumatoid arthritis (RA), 20 patients with classical or definite RA as determined by ARA criteria and twenty healthy volunteers serving as control were randomly selected. None of the patients showed the clinical signs suggesting Raynaud's phenomenon. Thermograms as well as photoelectric plethysmograms were obtained solely from the right middle finger tip of each examinee. The whole hand was then immersed in the cold (10℃) water and kept there for one minute. After wiping away the wet hand with a dry towel very gently, we followed the sequential changes of the tempe· rature of the third finger tip and the period of time necessary for the tip to return to the original temperature prior to the cold water immersion was measured and expressed as 'return time' in minute. Before exposure to the cold, the mean values of temperature of the finger tips between the two groups were not significantly different. As opposed to the normal pattern in which one can find the warmest point at the finger tip and which was more frequently found in the control group of the current study, a type in which the distal part of the finger was much cooler than the proximal area (so-called 'distal cold type') was observed in 8 RA patients, whereas only four demonstrated this pattern in the control group. After brief exposure to the cold, eight out of 20 rheumatoid patients showed much prolonged return time (longer than 20 minutes), while only three of 20 controls remained with prolonged cool periphery, The difference between the two, however, was not statistically significant. Studies of the digital plethysmograph revealed that 70% of all the rheumatoids showed abnormal patterns: sclerotic and monophasic waves were discovered in 55% of the patients. In contrast, seventy percent of the normal control demonstra· ted normal wave pattern. Although the significant difference was not noted, the mean height of the systolic peak of the plethysmograph derived from the rheumatoid group tended to be much reduced, suggesting the reduced blood volume at the finger tips. Six RA patients and 13 normals who showed normal plethysmographic pattern before immersion in the cold water, demonstrated rapid return to the original temperature. Only in one normal control with a normal wave pattern, prolonged return time was observed, although the height of the systolic peak of the plethysmogram in this particular case was well within normal limit. Digital circulatory disturbance, however, was strongly suspected in eight RA patients with severely prolonged return time, They all showed abnormal wave patterns of the plethysmogram, including 2 cases with peripheral plateau wave, Markedly reduced heights of the systolic peaks were also demonstrated in all. Further elaborate studies including digital arteriography were indicated to implicate any organic change in the digital vessels, such as digital arteritis in RA first reported by Bywaters in 1957.
en-copyright=
kn-copyright=

en-aut-name=OhtaTakamasa
en-aut-sei=Ohta
en-aut-mei=Takamasa
kn-aut-name=太田隆正
kn-aut-sei=太田
kn-aut-mei=隆正
aut-affil-num=1
ORCID=

en-aut-name=TokiokaMasaaki
en-aut-sei=Tokioka
en-aut-mei=Masaaki
kn-aut-name=時岡正明
kn-aut-sei=時岡
kn-aut-mei=正明
aut-affil-num=2
ORCID=

en-aut-name=TakasugiKiyoshi
en-aut-sei=Takasugi
en-aut-mei=Kiyoshi
kn-aut-name=高杉潔
kn-aut-sei=高杉
kn-aut-mei=潔
aut-affil-num=3
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学温泉研究所温泉医学部門

affil-num=2
en-affil=
kn-affil=岡山大学温泉研究所温泉医学部門

affil-num=3
en-affil=
kn-affil=岡山大学温泉研究所温泉医学部門
END

start-ver=1.4
cd-journal=joma
no-vol=46
cd-vols=
no-issue=
article-no=
start-page=11
end-page=14
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1977
dt-pub=19770325
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=A case of cancer in the gastric remnant
kn-title=残胃癌の1例
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=This is a report of cancer of the stomach encountered in a 71-year-old man who admitted to the hospital with complain of epigastralgia. He had undergo a two third gastrectomy with gastroduodenostomy 24 years before because of severe gastritis. For several years he had ambulatory treatment for diabetes mellitus, which was under good control. Laboratory examination revealed that red-cell count was 4,800,000, white-cell count 11,500 ; hemoglobin was 12.7gr. per 100ml, hematocrit 49.5 per cent. Total serum protein was 8.2%. The stool was positive for occult blood and the urine negative for protein. X-ray studies in barium filled stomach in upright position revealed a filling defect in the lessor curvature side. In the prone and supine double contrast studies, a lesion was visualized of irregular outline with marked surface unevenness. Endoscopically, a rough tumor resembling Borrman Type III cancer was found near the stoma on the anterior wall of gastric remnant. Marginal blending and convergency of the folds showing sudden cessation around the ulcer were recognized as well. These findings led the authors to the diagnosis of the cancer developing in the gastric remnant and total gastrectomy with esophagojejunostomia was performed. Reports of cancer in the gastric remnant detected more than 20 years after the first operation are so small in number.
en-copyright=
kn-copyright=

en-aut-name=NoishikiYasuharu
en-aut-sei=Noishiki
en-aut-mei=Yasuharu
kn-aut-name=野一色泰晴
kn-aut-sei=野一色
kn-aut-mei=泰晴
aut-affil-num=1
ORCID=

en-aut-name=NakaharaYasuhiro
en-aut-sei=Nakahara
en-aut-mei=Yasuhiro
kn-aut-name=仲原泰博
kn-aut-sei=仲原
kn-aut-mei=泰博
aut-affil-num=2
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学温泉研究所リハビリテーション医学部門

affil-num=2
en-affil=
kn-affil=岡山大学温泉研究所リハビリテーション医学部門
END

start-ver=1.4
cd-journal=joma
no-vol=46
cd-vols=
no-issue=
article-no=
start-page=1
end-page=9
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1977
dt-pub=19770325
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Fundamental study of post operative intestinal adhesion -Findings on early stage of peritoneal inflammation by ultraviolet irradiation-
kn-title=術後腸管癒着症の基礎的研究―紫外線刺激による腹膜の炎症の初期像―
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Early process of peritoneal inflammation on rat by ultraviolet irradiation was studied histologically and scanning electron microscopic· ally. After 1 minute irradiation of ultraviolet, minimal exudation on mesothelium was found. After 15 minutes irradiation, microvillies on mesothelium were covered with exudate. After 20 minutes, fibrin fibers appeared on intact mesothelium. Though the fibers wafted in exudate, the fibers could be cleared up by irrigation of saline. After 30 minutes, white and red cells appeared on the nest of fibrin fibers. After 45 minutes, edema came out at subserosal layer. After 1 hour, mesothelium was covered with fibrin fibers, white and red cells. But the coated fur could be washed off by jet irrigation of saline and intact mesothelium benearth the fur appeared. These results indicate that washing a peritoneal cavity by saline after abdominal operation is of practical value to prevent a intestinal adhesion due to post operative intestinal inflammation. Inflammatory changes of intestinal mesothlium was clearly demonstrated by scanning electron microscope and these observations revealed that scanning electron microscope was very useful for the study of inflammation which occured on the surfaces of organs.
en-copyright=
kn-copyright=

en-aut-name=NoishikiYasuharu
en-aut-sei=Noishiki
en-aut-mei=Yasuharu
kn-aut-name=野一色泰晴
kn-aut-sei=野一色
kn-aut-mei=泰晴
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学温泉研究所リハビリテーション医学部門
END

start-ver=1.4
cd-journal=joma
no-vol=46
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1977
dt-pub=19770325
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=目次
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=Institute for Thermal Spring Research, Okayama University
en-aut-sei=Institute for Thermal Spring Research, Okayama University
en-aut-mei=
kn-aut-name=岡山大学温泉研究所
kn-aut-sei=岡山大学温泉研究所
kn-aut-mei=
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=
END

start-ver=1.4
cd-journal=joma
no-vol=46
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1977
dt-pub=19770325
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=表紙
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=Institute for Thermal Spring Research, Okayama University
en-aut-sei=Institute for Thermal Spring Research, Okayama University
en-aut-mei=
kn-aut-name=岡山大学温泉研究所
kn-aut-sei=岡山大学温泉研究所
kn-aut-mei=
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=
END