start-ver=1.4 cd-journal=joma no-vol=54 cd-vols= no-issue=3-4 article-no= start-page=233 end-page=239 dt-received= dt-revised= dt-accepted= dt-pub-year=2006 dt-pub=20064 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Elucidation of the role of the complex in hydride transfer reaction between methylene blue and 1-benzyl-1,4-dihydronictinamide by effect of γ-cyclodextrin en-subtitle= kn-subtitle= en-abstract= kn-abstract=

The kinetics of the hydride transfer reaction between Methylene Blue (MB+) and　1-benzyl-1,4-dihydronicotinamide (BNAH) were studied in 10 % ethanol-90 % water mixed solvents containing β- and γ-cyclodextrins (β-CD and γ-CD). The pseudo-first order rate constant shows kinetic saturation at high initial concentration of BNAH. This indicates the formation of a complex between MB+ and BNAH. The reaction was suppressed by addition of β-CD, but enhanced by addition of γ-CD. MB+ and BNAH were separately accommodated within the β-CD cavity and the cavity walls may protect the activity site of the reactants. On the other hand, in the MB+-BNAH-γ-CD system, the inclusion of the complex between MB+ and BNAH with γ-CD occurred. This effect of γ-CD can distinguish between the productive and non-productive nature of the complex.

en-copyright= kn-copyright= en-aut-name=LiuYingin en-aut-sei=Liu en-aut-mei=Yingin kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=HotouchiNaoto en-aut-sei=Hotouchi en-aut-mei=Naoto kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=SueishiYoshimi en-aut-sei=Sueishi en-aut-mei=Yoshimi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=YamamotoShunzo en-aut-sei=Yamamoto en-aut-mei=Shunzo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= affil-num=1 en-affil= kn-affil=Okayama University affil-num=2 en-affil= kn-affil=Okayama University affil-num=3 en-affil= kn-affil=Okayama University affil-num=4 en-affil= kn-affil=Okayama University en-keyword=hydride transfer reaction kn-keyword=hydride transfer reaction en-keyword=reaction mechanism kn-keyword=reaction mechanism en-keyword=cyclodextrin kn-keyword=cyclodextrin en-keyword=inclusion complexes kn-keyword=inclusion complexes en-keyword=1-benzyl-1 kn-keyword=1-benzyl-1 en-keyword=4-dihydronicotinamide kn-keyword=4-dihydronicotinamide en-keyword=Methylene Blue kn-keyword=Methylene Blue END