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ID 31040
JaLCDOI
フルテキストURL
著者
Yabe, Yoshiro Okayama University
Matsumoto, Kyoko Okayama University
Ogura, Hajime Okayama University
抄録

To establish an experimental persistent infection of the brain with human adenoviruses, adenovirus type 6 (ad 6) was inoculated intracerebrally into young adult hamsters. Hamsters appeared languid for a few days after inoculation, but recovered rapidly. By cocultivation of tissue fragments with HeLa cells, ad 6 was always recovered from the brains of hamsters throughout their lives, as long as 29 months, indicating the establishment of a lifelong persistent infection. Except for the first few days after inoculation, however, attempts to recover virus by inoculation of tissue extracts onto HeLa cells or by cultivation of tissue fragments alone were unsuccessful.

キーワード
adenovirus type 6
persistent infection
hamster brain
Amo Type
Article
発行日
1988-02
出版物タイトル
Acta Medica Okayama
42巻
1号
出版者
Okayama University Medical School
開始ページ
45
終了ページ
47
ISSN
0386-300X
NCID
AA00508441
資料タイプ
学術雑誌論文
言語
English
論文のバージョン
publisher
査読
有り
PubMed ID
Web of Sience KeyUT