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ID 42484
フルテキストURL
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タイトル(別表記)
Studies on Alkylphosphate Poisoning Part I Experimental Studies on the Toxicity of Alkylphosphate
著者
山田 稔 岡山大学医学部平木内科教室
抄録
The toxicity of emulsified methylparathion, diazinon, chlorthion and sumicide examined in comparison with that of ethylparathion in laboratory rabbit. The results were as follows. 1) All these compounds were absorbed by means of dermal, oral, subcutaneous snd intravenous application. Methylparathion was 1/21/4, chlorthion was 1/31/8 and sumicide was 1/25 as toxic as ethylparathion, but diazinon was toxic as much the same. 2) These compounds produced a marked depression of cholinesterase (ChE) activities of both serum and red blood cell in all subjects examined. The ChE inactivation caused by methylparathion and sumicide slower than that of the others. 3) The main symptoms caused by exposure to these compounds were alike to those produced by ethylparathion. 4) With the application of these compouuds, the changes of hemoglobin and red blood cell count were not remarkable, except in the sumicide case which the decrease of both occured 2 to 3 days after the administration. There occured, as the case of ethylparathion, leucocytosis, mainly occupied by pseudoeosinophils with the deflection of Arneth count to the left as well as relative lymphocytopenia.
発行日
1957-02-28
出版物タイトル
岡山医学会雑誌
出版物タイトル(別表記)
Journal of Okayama Medical Association
69巻
2号
出版者
岡山医学会
出版者(別表記)
Okayama Medical Association
開始ページ
501
終了ページ
514
ISSN
0030-1558
NCID
AN00032489
資料タイプ
学術雑誌論文
オフィシャル URL
https://www.jstage.jst.go.jp/article/joma1947/69/2/69_2_501/_article/-char/ja/
関連URL
http://www.okayama-u.ac.jp/user/oma/
言語
Japanese
著作権者
Copyright© 岡山医学会
論文のバージョン
publisher
査読
有り
Eprints Journal Name
joma