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ID 14017
Eprint ID
14017
フルテキストURL
Thumnail 105_265.pdf 685 KB
タイトル(別表記)
Clinical studies on hypoplastic anemia in the aged
著者
植田 育寛 岡山大学医学部第二内科学教室
抄録
To evaluate hypoplastic anemia (HA) in the aged, clinical and hematological findings of 88 patients with HA were analyzed. The patients were classified into 4 groups according to age (Group A : 5-24 y/o, Group B : 25-44 y/o, Group C : 45-64 y/o and Group D : 65 y/o- ). Hematological findings of patients in Group D were also compared to those of aged patients (above 65 y/o) with myelodisplastic syndrome (MDS) to clarify differentiation of HA from MDS. Items studied were severity, therapeutic response, complications, hematological findings, survival period and cause of death. The following results were obtained : 1. HA in the aged was frequently severe. 2. Responses to therapies including anabolic steroids and corticosteroids tended to be poor in the aged compared to those in younger patients. 3. Infections and diabetes mellitus were frequently observed complications in the aged. 4. Mortality in the aged was higher than that in younger patients. 57.1% of the aged died from bleeding. 5. The survival period of patients in Group C and D was shorter than that of patients in Group A and B. 6. Red blood cell count, reticulocytes and hemoglobin level in the aged were significantly lower than those in younger patients. Neutrophil and monocyte counts in the aged tended to be lower than those in younger patients. Nucleated cell counts and percentages of granulocytes and erythroblasts in the marrow were also lower in the aged. 7. The incidence of atypical hematological findings in HA were not different between the aged and younger patients. 8. In a comparison of HA in Group D and MDS in the aged, patients with HA showed severe anemia and thrombocytopenia.
キーワード
再生不良性貧血
高齢者貧血
骨髄異形成症候群
発行日
1993
出版物タイトル
岡山医学会雑誌
出版物タイトル(別表記)
Journal of Okayama Medical Association
105巻
3-4号
出版者
岡山医学会
出版者(別表記)
Okayama Medical Association
開始ページ
265
終了ページ
279
ISSN
0030-1558
NCID
AN00032489
資料タイプ
学術雑誌論文
オフィシャル URL
https://www.jstage.jst.go.jp/article/joma1947/105/3-4/105_3-4_265/_article/-char/ja/
関連URL
http://www.okayama-u.ac.jp/user/oma/index.html
言語
Japanese
著作権者
岡山医学会
論文のバージョン
publisher
査読
有り
Eprints Journal Name
joma