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ID 32815
JaLCDOI
フルテキストURL
著者
Saika, Takashi Okayama University
Tsushima, Tomoyasu Okayama University
Nasu, Yasutomo Okayama University Kaken ID researchmap
Arata, Ryoji Okayama University
Kaku, Haruki Okayama University
Akebi, Naoki Okayama University
Kusaka, Nobuyuki Okayama University
Kumon, Hiromi Okayama University
抄録

The aim of this study was to reveal the clinical features of anterior urethral recurrence in patients with superficial bladder cancer, and to determine the appropriate treatment. Three hundred and three patients with superficial bladder cancer, who were newly diagnosed and initially treated conservatively in our hospital between 1965 and 1990, were followed for at least 5 years and their clinical outcomes were analyzed. Clinical factors, including anterior urethral recurrence, were evaluated statistically regarding tumor progression. Eight patients (2.6%) had anterior urethral recurrence following superficial bladder cancer. Twenty-four patients (7.9%) had tumor progression and 149 (49.2%) had tumor recurrence. In a multivariate analysis using a logistic model, anterior urethral recurrence was the most important factor, followed by histological grade. Four of 5 patients who were treated for anterior urethral recurrent tumors by transurethral resection showed progression and died of the cancer within one year. Two of the remaining three patients who underwent radical cysto-urethrectomy at the time of anterior urethral recurrence survived. Anterior urethral recurrence following superficial bladder cancer is a predictor for rapid subsequent malignant progression. Once there is anterior urethral recurrence, radical intensive therapy, including radical cysto-urethrectomy, should be carried out immediately.

キーワード
superficial bladder cancer
anterior urehral recurrence
prognosis
predictor
Amo Type
Article
発行日
2003-12
出版物タイトル
Acta Medica Okayama
57巻
6号
出版者
Okayama University Medical School
開始ページ
293
終了ページ
297
ISSN
0386-300X
NCID
AA00508441
資料タイプ
学術雑誌論文
言語
English
論文のバージョン
publisher
査読
有り
PubMed ID
Web of Science KeyUT