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ID 30563
JaLCDOI
フルテキストURL
Thumnail fulltext.pdf 2.02 MB
著者
Yamada, Teruo Okayama University
Talbot, Alan Okayama University
Hirakawa, Misahisa Okayama University
Kobayashi, Naohide Okayama University
Shiwaku, Yoshitomo Okayama University
Kosaka, Futami Okayama University
Kimoto, Tetsuo Kawasaki Medical School
抄録
Renal cortex was studied during experimentally induced ischemia. A transient increase in anerobic glycolysis occurred with concomitant swelling of both the Golgi apparatus and mitochondria. These intracytoplasmic organelles underwent marked changes in their intracellular positions. Infolding of cytoplasmic membrane at the basal side of proximal tubule cells increased in complexity and proceeded to enclose various intracytoplasmic microorganelles such as mitochondria and the Golgi apparatus. Piling up in layers was particularly marked around mitochondria. This piling up appeared as myelin-like structures on the free surface of, and within, proximal tubule cells, and followed disruption of the brush border at the free surface. Histological examination of thin sections showed that the fused portions of this brush border were actually brush border cytoplasmic membrane piled up in layers giving the appearance of myelin-like structures. After two hours of ischemia, parts of the membrane of these myelin-like structures were disrupted. Large vacuoles developed and these were thought to be related to the large vacuoles seen during cell degeneration.
キーワード
Myelin-like structures
ischemia
kidney
Amo Type
Article
発行日
1980-02
出版物タイトル
Acta Medica Okayama
34巻
1号
出版者
Okayama University Medical School
開始ページ
19
終了ページ
30
ISSN
0386-300X
NCID
AA00508441
資料タイプ
学術雑誌論文
言語
English
論文のバージョン
publisher
査読
有り
PubMed ID
Web of Sience KeyUT