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ID 41327
JaLCDOI
フルテキストURL
Thumnail 64_6_407.pdf 1.78 MB
著者
Ogata, Sho Department of Pathology and Laboratory Medicine, National Defense Medical College
Horio, Takuya Department of Surgery II, National Defense Medical College
Sugiura, Yoshiaki Department of Surgery, International University of Health and Welfare Mita Hospital
Shimazaki, Hideyuki Department of Laboratory Medicine, National Defense Medical College
Saito, Hiroki Department of Surgery II, National Defense Medical College
Aiko, Satoshi Department of Surgery II, National Defense Medical College
Nakanishi, Kuniaki Department of Pathology and Laboratory Medicine, National Defense Medical College
Kawai, Toshiaki Department of Pathology and Laboratory Medicine, National Defense Medical College
抄録
Sarcoidosis is a systemic granulomatous inflammation of unknown etiology, and seems to involve the liver parenchyma in most cases. However, sarcoidosis-associated hepatocellular carcinoma is rare. We report here a case in which a hepatocellular carcinoma occurred within the liver, which was probably involved as a result of systemic sarcoidosis. A 57-year-old Japanese man had been followed up for 2 years because of diabetic nephropathy and sarcoidosis. On admission for pneumonia, imaging studies revealed an unexpected hepatic tumor. Histology revealed a hepatocellular carcinoma accompanied by T-lymphocytic infiltration and marked granulomatous inflammation, which was surrounding some tumor nodules. The background liver parenchyma exhibited a moderate degree of fibrosis with granulomatous inflammation. The patient had no other apparent liver disease such as viral hepatitis, steatohepatitis, or primary biliary cirrhosis. Therefore, in the present case, sarcoidosis may be considered the probable background etiology for hepatocarcinogenesis.
キーワード
granuloma
hepatocellular carcinoma
lymphocytic infiltration
sarcoidosis
Amo Type
Case Report
発行日
2010-12
出版物タイトル
Acta Medica Okayama
64巻
6号
出版者
Okayama University Medical School
開始ページ
407
終了ページ
410
ISSN
0386-300X
NCID
AA00508441
資料タイプ
学術雑誌論文
言語
English
著作権者
Okayama University Medical School
論文のバージョン
publisher
査読
有り
PubMed ID
Web of Sience KeyUT