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ID 51049
フルテキストURL
著者
Suzuki, Hideyuki
Kato, Jun Okayama Univ, Grad Sch Med Dent & Pharmaceut Sci, Dept Gastroenterol & Hepatol
Kuriyama, Motoaki
Hiraoka, Sakiko
Kuwaki, Kenji
Yamamoto, Kazuhide
抄録
AIM: To identify specific colonoscopic findings in patients with ulcerative colitis (UC) complicated by cytomegalovirus (CMV) infection. METHODS: Among UC patients who were hospitalized due to exacerbation of symptoms, colonoscopic findings were compared between 15 CMV-positive patients and 58 CMV-negative patients. CMV infection was determined by blood test for CMV antigenemia. Five aspects of mucosal changes were analyzed (loss of vascular pattern, erythema, mucosal edema, easy bleeding, and mucinous exudates) as well as five aspects of ulcerative change (wide mucosal defect, punched-out ulceration, longitudinal ulceration, irregular ulceration, and cobblestone-like appearance). Sensitivity, specificity, positive predictive value, and negative predictive value of each finding for CMV positivity were determined. RESULTS: The sensitivity of irregular ulceration for positive CMV was 100%. The specificity of wide mucosal defect was 95%. Punched-out ulceration and longitudinal ulceration exhibited relatively high sensitivity and specificity (more than 70% for each). CONCLUSION: Specific colonoscopic findings in patients with UC complicated by CMV infection were identified. These findings may facilitate the early diagnosis of CMV infection in UC patients.
キーワード
Cytomegalovirus
Endoscopic findings
Ulcerative colitis
発行日
2010-03-14
出版物タイトル
World Journal of Gastroenterology
16巻
10号
開始ページ
1245
終了ページ
1251
ISSN
1007-9327
資料タイプ
学術雑誌論文
オフィシャル URL
http://dx.doi.org/10.3748/wjg.v16.i10.1245
関連URL
http://ousar.lib.okayama-u.ac.jp/metadata/50670
言語
English
著作権者
(C) 2010 Baishideng. All rights reserved.
論文のバージョン
publisher
査読
有り
DOI
Web of Sience KeyUT