JaLCDOI 10.18926/AMO/57379
フルテキストURL 73_5_469.pdf
著者 Yamasaki, Satoshi| Kada, Akiko| Nagai, Hirokazu| Yoshida, Isao| Choi, Ilseung| Saito, Akiko M.| Iwasakia, Hiromi|
抄録 Romidepsin is an important therapeutic option for patients with peripheral T-cell lymphoma (PTCL). However, the timing of romidepsin administration remains controversial. Romidepsin was launched in Japan as a consolidation therapy agent after conventional salvage chemotherapy with gemcitabine, dexamethasone, and cisplatin (GDP). GDP therapy will be administered every 3 weeks. If complete response, partial response, or stable disease is confirmed after 2-4 GDP cycles, romidepsin will be administered every 4 weeks. The primary endpoint is a 2-year progression-free survival rate. Patients participating in this study and undergoing treatment can expect results similar to or better than those of conventional therapies.
キーワード peripheral T-cell lymphoma not otherwise specified angioimmunoblastic T-cell lymphoma gemcitabine cisplatin, romidepsin
Amo Type Clinical Study Protocol
発行日 2019-10
出版物タイトル Acta Medica Okayama
73巻
5号
出版者 Okayama University Medical School
開始ページ 469
終了ページ 474
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 English
著作権者 CopyrightⒸ 2019 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 31649375
Web of Sience KeyUT 000491886600014
JaLCDOI 10.18926/AMO/56381
フルテキストURL 72_6_611.pdf
著者 Tsunoda, Koichi| Kobayashi, Rika| Kada, Akiko| Saito, Akiko M.| Misawa, Hayato| Horibe, Keizo| Goto, Fumiyuki| Tsunoda, Atsunobu| Sasaki, Toru| Takanosawa, Minako| Nishino, Hiroshi| Kondoh, Kenji| Sugiyama, Yoichiro| Hisa, Yasuo|
抄録 The oropharynx is examined with a light source such as an electric light, a penlight, or a forehead mirror based on an acquired visual field using a tongue depressor. However, it is extremely difficult to obtain objective and reproducible images of tissue within the pharynx required in recent years with these methods, and insufficient progress in the examination tools has been made. There is an increasing need to develop a method for display during oropharyngeal examination. We conducted the present study to develop a novel oropharyngeal endoscope as an objective observation method.
キーワード tongue depressor oropharyngeal scope oral pharyngeal otorhinolaryngology
Amo Type Clinical Study Protocol
発行日 2018-12
出版物タイトル Acta Medica Okayama
72巻
6号
出版者 Okayama University Medical School
開始ページ 611
終了ページ 614
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 English
著作権者 CopyrightⒸ 2018 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 30573918
NAID 120006545166
JaLCDOI 10.18926/AMO/56186
フルテキストURL 72_4_441.pdf
著者 Kida, Daihei| Hashimoto, Hiroya| Saito, Akiko M.| Kito, Yukari| Mori, Kouichi| Terabe, Kenya| Takahashi, Nobunori| Tomita, Yasushi|
抄録 There is no assistive device for extramedullary surgery coordinated with 3D surgical assistive software for the total knee arthroplasty (TKA). We developed a novel extramedullary universal guide coordinated with 3D surgical assistive software and a novel extramedullary patient-specific assistive guide for the placement of femoral components by referring to an area not affected by cartilage or bone spurs, and filed a patent application. In this study, we visualize and reconstruct the total alignment of the lower extremity in TKA using these surgical devices, and validate their precision. A report releasing study results will be submitted in an appropriate journal.
キーワード total knee arthroplasty 3D surgical assistive software tibia femur extramedullary guide
Amo Type Clinical Study Protocol
発行日 2018-08
出版物タイトル Acta Medica Okayama
72巻
4号
出版者 Okayama University Medical School
開始ページ 441
終了ページ 445
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 English
著作権者 CopyrightⒸ 2018 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 30140096
JaLCDOI 10.18926/AMO/56185
フルテキストURL 72_4_437.pdf
著者 Koga, Yuhki| Baba, Shingo| Fukano, Reiji| Nakamura, Katsumasa| Soejima, Toshinori| Maeda, Naoko| Sunami, Shosuke| Ueyama, Junichi| Mitsui, Tetsuo| Mori, Takeshi| Osumi, Tomoo| Sekimizu, Masahiro| Ohki, Kentaro| Tanaka, Fumiko| Kamei, Michi| Fujita, Naoto| Mori, Tetsuya| Saito, Akiko M.| Kada, Akiko| Kobayashi, Ryoji|
抄録 This trial enrolls patients with untreated Hodgkin’s lymphoma aged<20 years at diagnosis and examines the effects of omitting radiation therapy if the FDG-positron emission tomography (PET) findings after two completed cycles of combination chemotherapy are negative. It thereby aims to determine whether patients who truly require radiation therapy can be identified by FDG-PET. If so, this modality could be used to omit radiation therapy for all other patients, decreasing the risk of serious long-term complications without affecting survival rates. The outcomes of patients for whom FDG-PET is used to assess early treatment response will also be determined.
キーワード Hodgkin’s lymphoma pediatric fludeoxyglucose positron emission tomography
Amo Type Clinical Study Protocol
発行日 2018-08
出版物タイトル Acta Medica Okayama
72巻
4号
出版者 Okayama University Medical School
開始ページ 437
終了ページ 440
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 English
著作権者 CopyrightⒸ 2018 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 30140095
JaLCDOI 10.18926/AMO/55863
フルテキストURL 72_2_197_n.pdf
著者 Takase, Ken| Kada, Akiko| Iwasaki, Hiromi| Yoshida, Isao| Sawamura, Morio| Yoshio, Nobuyuki| Yoshida, Shinichiro| Iida, Hiroatsu| Otsuka, Maki| Takafuta, Toshiro| Ogata, Yuko| Suehiro, Youko| Hirabayashi, Yukio| Hishita, Terutoshi| Yoshida, Chikamasa| Ito, Takuo| Hidaka, Michihiro| Tsutsumi, Ikuyo| Saito, Akiko M.| Nagai, Hirokazu|
抄録 Standard therapy for idiopathic thrombocytopenic purpura (ITP) has not been established. We are conducting a multicenter, prospective trial to determine the efficacy and safety of short-term, high-dose dexamethasone therapy in ITP patients aged 18-80 years with platelet counts of <20, 000 /μL, or with <50, 000/ μL and bleeding symptoms. The primary endpoints of this trial are the proportion of responses (complete plus partial response) on day 180 (day 46+180) after the completion of the 46-day high-dose dexamethasone therapy. The results of this investigation of the effectiveness and safety of this regimen will be essential for the establishment of standard therapy for ITP.
キーワード idiopathic thrombocytopenic purpura short-term high-dose dexamethasone therapy open-label single-arm trial
Amo Type Clinical Study Protocol
発行日 2018-04
出版物タイトル Acta Medica Okayama
72巻
2号
出版者 Okayama University Medical School
開始ページ 197
終了ページ 201
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 English
著作権者 CopyrightⒸ 2018 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 29674771