フルテキストURL J_Cell_Biochem_116_10_2146.pdf
著者 Eguchi , Taka| Prince, Thomas| Wegiel, Barbara| Calderwood, Stuart K.|
抄録 Myeloid zinc finger 1 (MZF1) belongs to the SCAN-Zinc Finger (SCAN-ZF) transcription factor family that has recently been implicated in a number of types of cancer. Although the initial studies concentrated on the role of MZF1 in myeloid differentiation and leukemia, the factor now appears to be involved in the etiology of major solid tumors such as lung, cervical, breast, and colorectal cancer. Here we discuss the regulation of MZF1 that mediated its recruitment and activation in cancer, concentrating on posttranslational modification by phosphorylation, and sumoylation, formation of promyelocytic leukemia nuclear bodies and its association with co-activators and co-repressors.
キーワード CANCER FINGER-1 INVASION MYELOID NUCLEAR BODY SUMO ZINC
発行日 2015-04-21
出版物タイトル Journal of cellular biochemistry
116巻
10号
出版者 Wiley
開始ページ 2146
終了ページ 2154
ISSN 0730-2312
NCID AA1052210X
資料タイプ 学術雑誌論文
言語 Japanese
OAI-PMH Set 岡山大学
論文のバージョン author
PubMed ID 25903835
DOI 10.1002/jcb.25203
Web of Sience KeyUT 000359809400004
関連URL isVersionOf https://doi.org/10.1002/jcb.25203