JaLCDOI 10.18926/AMO/31124
フルテキストURL fulltext.pdf
著者 Ariki, Norifumi| Iwagaki, Hiromi| Yoshino, Tadashi| Nonaka, Yasuyuki| Fujiki, Shigeatsu| Perdomo, Jose Antonio| Hizuta, Akio| Tomoda, Jun| Tanaka, Noriaki| Tsuji, Takao| Orita, Kunzo|
抄録 <p>Endoscopical segmental piecemeal tumorectomy (ESPT) for nodular elevation of colorectal tumor is advantageous in terms of minimizing both surgical invasion and postoperative burden to the patients. Nodular elevation of colorectal tumors is said to occur when the body of the tumor is adenomatous and the surface of the focal cancer grows more horizontally into the lumen than vertically. We report here four cases of nodular elevation of colorectal tumors which were each treated by different surgical procedures.</p>
キーワード nodular elevation coloretal tumors endoscopical segmental piecemeal tumorectomy
Amo Type Article
発行日 1994-06
出版物タイトル Acta Medica Okayama
48巻
3号
出版者 Okayama University Medical School
開始ページ 169
終了ページ 171
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 English
論文のバージョン publisher
査読 有り
PubMed ID 7942075
Web of Sience KeyUT A1994NV04300009
JaLCDOI 10.18926/AMO/31094
フルテキストURL fulltext.pdf
著者 Iwagaki, Hiromi| Hizuta, Akio| Iwadou, Hironori| Perdomo, Jose Antonio| Tanaka, Noriaki| Orita, Kunzo|
抄録 <p>In this study, we investigated serum-soluble interleukin-2 receptor (sIL-2r) and neopterin (NPT) levels in five patients with severe postoperative infections. A total of 25 synchronous determinations of sIL-2r and NPT were performed. A marked increase in sIL-2r and NPT levels was observed, and the increase in sIL-2r was significantly correlated to that of NPT which is a marker of macrophage activity. These results suggest that macrophages are involved in the stimulation of sIL-2r release, representing a potentially negative biological effect. The results indicate that sIL-2r may be a useful indicator of the efficacy of antibiotics and of prognosis.</p>
キーワード soluble interleukin-2 receptor neopterin intection
Amo Type Article
発行日 1994-08
出版物タイトル Acta Medica Okayama
48巻
4号
出版者 Okayama University Medical School
開始ページ 225
終了ページ 226
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 English
論文のバージョン publisher
査読 有り
PubMed ID 7817778
Web of Sience KeyUT A1994PE51400008
JaLCDOI 10.18926/AMO/31090
フルテキストURL fulltext.pdf
著者 Perdomo, Jose Antonio| Iwagaki, Hiromi| Hizuta, Akio| Tanaka, Noriaki| Orita, Kunzo|
抄録 <p>Familial adenomatous polyposis (FAP) is a well-known autosomal dominant disorder characterized by the formation of multiple adenomatous polyps of the colon. Gardner's syndrome is a variant of familial polyposis coli, and both can be associated with colonic or extracolonic benign and/or malignant tumors. It has been widely recognized that an adenocarcinoma of the colon develops in virtually all cases, usually at an earlier age, if polyps are left untreated. Families of four individuals diagnosed of FAP were surveyed and 56 relatives of the families were examined. Of these 56, 21 had multiple colon polyps, 3 of whom had early-stage adenocarcinomas. We consider that familial survey of FAP individuals can be of considerable benefit for this high-risk population due to the autosomal nature of the disease, allowing diagnosis of an associated cancer at an earlier stage.</p>
キーワード familial adenomatous polyposis colorectal carcinoma Gardner's syndrome
Amo Type Article
発行日 1994-08
出版物タイトル Acta Medica Okayama
48巻
4号
出版者 Okayama University Medical School
開始ページ 227
終了ページ 229
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 English
論文のバージョン publisher
査読 有り
PubMed ID 7817779
Web of Sience KeyUT A1994PE51400009
JaLCDOI 10.18926/AMO/30494
フルテキストURL fulltext.pdf
著者 Iwagaki, Hiromi| Hizuta, Akio| Fujiwara, Toshiyushi| Perdomo, Jose Antonio| Tanaka, Noriaki| Orita, Kunzo|
抄録 <p>Patients with far advanced colorectal cancers received chemotherapy consisting of low-dose cyclophosphamide (LDCY) 333 mg/m2 every four weeks intravenously and by oral administration of 5'-DFUR (a masked compound of 5-Fluorouracil). Serum levels of immunosuppressive acidic protein (IAP), an acute phase protein, were measured every four weeks for a total of thirty-one LDCY trials of ten patients. LDCY chemotherapy significantly decreased the IAP levels in cancer patients with high IAP levels. These results suggested that LDCY chemotherapy could counteract host responses against tumors and could have decreased immunosuppressive responses in cancer patients.&#60;/P&#62;</p>
キーワード low-dose cyclophosphamide< acute phase protein immunosuppressive acidic protein
Amo Type Article
発行日 1996-10
出版物タイトル Acta Medica Okayama
50巻
5号
出版者 Okayama University Medical School
開始ページ 271
終了ページ 272
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 English
論文のバージョン publisher
査読 有り
PubMed ID 8914681
Web of Sience KeyUT A1996VQ20600007
JaLCDOI 10.18926/AMO/30394
フルテキストURL fulltext.pdf
著者 Perdomo, Jose Antonio| Iwagaki, Hiromi| Hizuta, Akio| Mizuno, Motowo| Nakagawa, Hitoshi| Tanaka, Noriaki| Tsuji, Takao| Orita, Kunzo|
抄録 <p>The medical records of 16 consecutive patients with Crohn's disease surgically treated in our department from 1978 to 1993 were retrospectively reviewed. The indication for surgery was obstructive symptoms due to Crohn's strictures that were unresponsive to conservative therapy. The types of operations performed were classified into five categories. Nine patients (56.3%) had small bowel resection only, 4 (25.0%) underwent an ileocolonic resection, 1 (6.3%) had a total colectomy, 1 (6.3%) had Mile's operation and 1 (6.3%) had subtotal gastrectomy with gastrojejunostomy and antral mucosectomy. Of these 16 patients, 13 (81.3%) had resection with a single anastomosis and strictureplasty was concomitantly performed in only 2 cases (12.5%). Crohn's disease recurred in 3 patients (18.8%), 1 of whom required a second operation.</p>
キーワード Crohn's disease surgical resection strictureplasty recurrence
Amo Type Article
発行日 1995-04
出版物タイトル Acta Medica Okayama
49巻
2号
出版者 Okayama University Medical School
開始ページ 113
終了ページ 115
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 English
論文のバージョン publisher
査読 有り
PubMed ID 7618489
Web of Sience KeyUT A1995QV69800008