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ID 40135
JaLCDOI
フルテキストURL
著者
Pavelić, Jasminka Division of Molecular Medicine, Laboratory of Molecular Oncology, Ruđer Bošković Institute
Čulić, Srdjana Clinical Department for Hematology, Oncology, Immunology and Medical Genetics, Clinical Hospital Center Split, Paediatric Clinic
Čulić, Vida Clinical Department for Hematology, Oncology, Immunology and Medical Genetics, Clinical Hospital Center Split, Paediatric Clinic
抄録
The occurrence of Langerhans cell histiocytosis (LCH) and another malignancy in the same patient is infrequent but has been recognized. The genetic changes that could be responsible for LCH and/or concomitant leukemia development are obscure. To the best of our knowledge, this is the first description of constitutional maternally derived inv (9) (p12;q13) in an LCH patient, and also of the development of common ALL Ph after LCH diagnosis and therapy. The potential significance of these findings [inv (9)LCHALL Ph] and their mutual relationship are unknown. Therefore, cooperative studies of large numbers of patients are needed to identify the common risk factors, if any.
キーワード
acute lymphoblastic leukemia
genetic changes
langerhans cell histiocytosis
Amo Type
Case Report
発行日
2010-08
出版物タイトル
Acta Medica Okayama
64巻
4号
出版者
Okayama University Medical School
開始ページ
263
終了ページ
265
ISSN
0386-300X
NCID
AA00508441
資料タイプ
学術雑誌論文
言語
English
著作権者
Okayama University Medical School
論文のバージョン
publisher
査読
有り
PubMed ID
Web of Sience KeyUT