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ID 32860
JaLCDOI
フルテキストURL
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著者
Ogata, Sho Department of Pathology and Laboratory Medicine, National Defense Medical College
Kimura, Akifumi Department of Surgery III, National Defense Medical College
Hatsuse, Kazuo Department of Surgery III, National Defense Medical College
Yamamoto, Junji Department of Surgery III, National Defense Medical College
Shimazaki, Hideyuki Department of Laboratory Medicine, National Defense Medical College
Nakanishi, Kuniaki Department of Pathology and Laboratory Medicine, National Defense Medical College
Kawai, Toshiaki Department of Pathology and Laboratory Medicine, National Defense Medical College
抄録

Poorly differentiated adenocarcinoma without papilla or tubule formation of the extrahepatic bile duct is rare. Here we present a case (a 42-year-old Japanese woman) without either pancreatobiliary maljunction or liver disease. The patient had obstructive jaundice. Imaging studies revealed a bile duct tumor obstructing the common bile duct and invading the surrounding tissues. Pathologic examination revealed a dense periductal growth of poorly differentiated adenocarcinoma containing signet-ring cells, but without papilla or tubule formation in the extrahepatic bile duct. The tumor cells directly invaded the pancreatic parenchyma and the portal vein. In the extrahepatic bile duct, poorly differentiated adenocarcinoma may be established as a distinct clinicopathologic entity if the tumors are characterized by:1) the absence of papilla or tubule formation, 2) Asian preponderance, 3) occurrence at a younger age than is usual for patients with biliary cancers, and 4) an aggressive mural invasiveness.

キーワード
adenocarcinoma
bile duct cancer
signet-ring cell carcinoma
Amo Type
Case Report
発行日
2010-02
出版物タイトル
Acta Medica Okayama
64巻
1号
出版者
Okayama University Medical School
開始ページ
63
終了ページ
65
ISSN
0386-300X
NCID
AA00508441
資料タイプ
学術雑誌論文
言語
English
論文のバージョン
publisher
査読
有り
PubMed ID
Web of Science KeyUT