JaLCDOI 10.18926/AMO/32430
フルテキストURL fulltext.pdf
著者 Harada, Hideo| Hayashi, Toshiaki| Miki, Hiroshi| Miyake, Hirofumi| Ochi, Kozi| Kimura, Ikuro| Takeda, Masahiko| Tanaka, Juntaro| Tanaka, Toshio|
抄録 <p>Sulfated acidic mucopolysaccharides have been found to be significant components of &#34;protein plugs&#34; in patients with chronic pancreatitis. The precise identification of the mucopolysaccharides and their distribution within the protein plugs may clarify the pathogenesis of the plugs. Pure pancreatic juice from five patients with chronic pancreatitis was obtained by endoscopic retrograde catheterization of the papilla of Vater. Enzymes for digestion of the plugs included hyaluronidase of the bovine testes and streptomyces hyalurolyticus, chondroitinase ABC and AC, and sialidase (neuraminidase). Our study indicated that: I) Sialic acid is distributed throughout the plugs and may be a major component, followed by a lesser amount of chondroitin sulfate B. 2) Chondroitin sulfate A, C, D and E and chondroitin may be minor components. 3) Hyaluronic acid is negligible in the plugs.</p>
キーワード chronic pancreatitis pure pancreatic juice protein plugs enzyme-histochemistry
Amo Type Article
発行日 1983-06
出版物タイトル Acta Medica Okayama
37巻
3号
出版者 Okayama University Medical School
開始ページ 227
終了ページ 231
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 English
論文のバージョン publisher
査読 有り
PubMed ID 6224398
Web of Sience KeyUT A1983QW75400006