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ID 13780
Eprint ID
13780
フルテキストURL
Thumnail 106_789.pdf 1.27 MB
タイトル(別表記)
Human T-lymphotropic virus type-Ⅰinfection and pulmonary fibrosing changes in patients with lung cancer
著者
難波 靖治 岡山大学医学部第二内科学教室
抄録
Thirty-one patients with lung cancer in Okinawa known as HTLV-Ⅰendemic area, and 140 patients in Okayama were evaluated in regard to HTLV-Ⅰinfection and iterstitial pulmonary shadows. The presence of HTLV-Ⅰinfection was examined by the polymerase chain reaction (PCR) method in peripheral blood mononuclear cells, and indirect immunofluorescent (IF) assay in sera. Interstitial pulmonary shadows on the chest roentgenograph, were classified according to the grade of fibrosis. The rate of HTLV-Ⅰinfection in patients with lung cancer was higher than that in healthy controls by IF assay in both districts. The rate of anti-HTLV-Ⅰantibody was higher in lung cancer patients with severe fibrosis than in those with milder fibrosis, but the grade of fibrosis and existence of pX gene had no relation in Okinawa or in Okayama. The incidence of patients with anti-HTLV-Ⅰantibody was higher in patients with adenocarcinoma and squamous cell carcinoma than in those with small cell carcinoma. These findings suggested that HTLV-Ⅰinfection was closely involved in some patients with non-small cell lung cancer having intersitital pulmonary shadows.
キーワード
肺癌
びまん性間質性肺病変
polymerase chain reaction
間接蛍光抗体法
HTLV-Ⅰ
備考
原著
発行日
1994-08
出版物タイトル
岡山医学会雑誌
出版物タイトル(別表記)
Journal of Okayama Medical Association
106巻
7-8号
出版者
岡山医学会
出版者(別表記)
Okayama Medical Association
開始ページ
789
終了ページ
798
ISSN
0030-1558
NCID
AN00032489
資料タイプ
学術雑誌論文
オフィシャル URL
https://www.jstage.jst.go.jp/article/joma1947/106/7-8/106_7-8_789/_article/-char/ja/
関連URL
http://www.okayama-u.ac.jp/user/oma/index.html
言語
Japanese
著作権者
岡山医学会
論文のバージョン
publisher
査読
有り
Eprints Journal Name
joma