JaLCDOI 10.18926/AMO/32863
フルテキストURL fulltext.pdf
著者 Murao, Wataru| Wada, Koichiro| Matsumoto, Akira| Fujiwara, Michihisa| Fukushi, Hideto| Kishimoto, Toshio| Monden, Koichi| Kariyama, Reiko| Kumon, Hiromi|
抄録 <p>In 2000, chlamydial strains OK133 and OK135 were isolated from 2 female patients with cervicitis. These strains were unresponsive to commercially available PCR and LCR test kits for the diagnosis of Chlamydia trachomatis infection, and their phenotypic characteristics were very similar. The OK135 nucleotide sequence in MOMP-VD2 gene closely resembled that of Chlamydophila caviae GPIC. A similar strain was isolated in 2003 from a male patient OKM2 with urethritis, from which the strain SC10-6 was cloned by the plaque purification method. The nucleotide sequence of the entire MOMP gene of SC10-6 was exactly the same as that of OK135. Thus, the strains OK135 and SC10-6, together with OK133, have been called C. caviae-like Chlamydia. We designed primers for nested PCR assay, the product of which showed a single-band 311-bp fragment, to detect C. caviae-like Chlamydia. Of swab specimens obtained from 202 patients from 2003 to 2006 (119 male and 83 female patients), 18 specimens (8.9%) from 14 male and 4 female patients were positive, suggesting that C. caviae-like Chlamydia infection is rather common. Thus far, it has not been determined whether C. caviae-like Chlamydia is pathogenic for humans.</p>
キーワード Chlamydophila caviae-like Chlamydia urethra uterine cervix epidemiology sexually transmitted infection
Amo Type Original Article
発行日 2010-02
出版物タイトル Acta Medica Okayama
出版者 Okayama University Medical School
開始ページ 1
終了ページ 9
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 English
論文のバージョン publisher
査読 有り
PubMed ID 20200578
Web of Science KeyUT 000274868300001