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ID 30386
JaLCDOI
フルテキストURL
著者
Zhao, Yi Guangxi College of TCM
Wang, Xiaoyan Okayama University
Kawai, Motoko Okayama University
Liu, Jiankang Okayama University
Liu, Miao Okayama University
Mori, Akitane Okayama University
抄録

Chinese ant extract preparations (CAEP) are a Chinese traditional medicine which is mainly used as a health food or drink for the treatment of rheumatism, rheumatoid arthritis, chronic hepatitis, sexual hypofunction, and antiaging in China. The effects on free radicals were examined by electron spin resonance spectrometry using the spin trapping agent 5.5-dimethyl-1-pyrroline-1-oxide (DMPO). Superoxide radicals (3.35 x 10(15) spins/ml) were quenched 50% by the extract at 0.5 mg/ml. The CAEP extract at 0.7 mg/ml inhibited 50% of hydroxyl radicals (52.0 x 10(15) spins/ml) generated by the Fenton reaction. Against DPPH radical, the scavenging action of CAEP was observed at 1.8 mg/ml of the extract and 50% of the DPPH radicals (8.14 x 10(15) spins/ml) were quenched. In vitro tests showed that CAEP inhibited the production of thiobarbituric acid-reactive substances, an index of lipid peroxidation, in rat brain homogenate.

キーワード
free radical scavenger
antioxidant
hydroxyl radical
superoxide radical
lipid peroxidation
Amo Type
Article
発行日
1995-12
出版物タイトル
Acta Medica Okayama
49巻
6号
出版者
Okayama University Medical School
開始ページ
275
終了ページ
279
ISSN
0386-300X
NCID
AA00508441
資料タイプ
学術雑誌論文
言語
English
論文のバージョン
publisher
査読
有り
PubMed ID
Web of Sience KeyUT