JaLCDOI 10.18926/AMO/43826
フルテキストURL 65_1_21.pdf
著者 Tamura, Hiroko| Suzue, Takeshi| Jitsunari, Fumihiko| Hirao, Tomohiro|
抄録 The aim of this study was to evaluate the carotid arterial intima-media thickness (IMT) and its relation to clinical parameters in Japanese children. Fifty-two healthy children (39 boys and 13 girls), aged 6-14 years, were enrolled in this cross-sectional investigation study. IMT of the common carotid artery was determined using ultrasonography. We also investigated anthropometric parameters, blood pressure (BP), lifestyles and blood examinations. The mean value of IMT was 0.4±0.1mm, which was lower than the normal value (1.0mm) in adults. IMT was positively correlated with age (r=0.340) and height (r=0.346) in boys, while it was positively correlated with body mass index (BMI) (r=0.584) and diastolic BP (DBP) (r=0.563) in girls. In addition, IMT was associated with sleeping hours and hours of watching television (TV) by using stepwise regression analysis. In conclusion, IMT increased with aging, and it was linked to some clinical parameters of atherosclerosis and lifestyles in children. Therefore, this reference data will be helpful for future assessment of age-related change in Japanese children in clinical practice, and IMT might be a good predictor of atherosclerosis in Japanese children.
キーワード intima-media thickness (IMT) lifestyle Japanese children proportional hazards models atherosclerosis
Amo Type Original Article
発行日 2011-02
出版物タイトル Acta Medica Okayama
65巻
1号
出版者 Okayama University Medical School
開始ページ 21
終了ページ 25
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 English
著作権者 CopyrightⒸ 2011 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 21339792
Web of Sience KeyUT 000287620500003
著者 Ogata, Masana| Nagao, Yutaka| Jitsunari, Fumihiko| Kitamura, Naoji| Okazaki, Tokio|
発行日 1970-04
出版物タイトル Acta Medicinae Okayama
24巻
2号
資料タイプ 学術雑誌論文
著者 Ogata, Masana| Nagao, Yutaka| Jitsunari, Fumihiko| Kikui, Ritsuko| Kitamura, Naoji|
発行日 1970-12
出版物タイトル Acta Medicinae Okayama
24巻
6号
資料タイプ 学術雑誌論文
著者 Ogata, Masana| Jitsunari, Fumihiko| Sunami, Shigeo| Hayashi, Sumiko|
発行日 1970-08
出版物タイトル Acta Medicinae Okayama
24巻
4号
資料タイプ 学術雑誌論文
著者 Ogata, Masana| Nagao, Yutaka| Jitsunari, Fumihiko| Kitamura, Naoji|
発行日 1969-12
出版物タイトル Acta Medicinae Okayama
23巻
6号
資料タイプ 学術雑誌論文
JaLCDOI 10.18926/AMO/30876
フルテキストURL fulltext.pdf
著者 Jitsunari, Fumihiko| Asakawa, Fumiyuki| Nakajima, Taichi| Shimada, Junko| Ogata, Masana|
抄録 <p>Chlorpyrifos, an organophosphorus insecticide, has been used to control termites since regulatory measures against the use of chlordanes were taken in September, 1986. We developed an improved gas chromatographic (GC) method for the assay of 3,5,6-trichloro-2-pyridinol (TCP) in the urine to use in the biological monitoring of exposure to chlorpyrifos. Urinary TCP was separated and determined accurately (C.V., 4%) with high sensitivity (detection limit, 10 ng/ml) and recovery (recovery greater than 90%) using a wide bore capillary column (WBC column). The accuracy and precision of the present GC method are satisfactory. The time course of urinary excretion of TCP was followed in workers. The urinary TCP level was low in the off-season and high in the busy season. Variation in the urinary TCP level corresponded to the termite control season and the length of the working period. The urinary TCP level showed a change reciprocal to the variations in the plasma cholinesterase activity. From these results, it is surmised that the urinary TCP level represents the extent of exposure to chlorpyrifos. The decrease in the level of cholinesterase activity is suggested to be due to exposure to chlorpyrifos. Determination of the urinary TCP level by GC using a WBC column is useful in the biological monitoring of chlorpyrifos in termite control workers and potentially has practical application to health care.</p>
キーワード termite control worker chlorpyrifos urinary 3 5 6-trichloro-2-pyridinol biological exposure index biological monitoring
Amo Type Article
発行日 1989-10
出版物タイトル Acta Medica Okayama
43巻
5号
出版者 Okayama University Medical School
開始ページ 299
終了ページ 306
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 English
論文のバージョン publisher
査読 有り
PubMed ID 2481940
Web of Sience KeyUT A1989CA06200006