JaLCDOI 10.18926/AMO/32371
フルテキストURL fulltext.pdf
著者 Ida, Noriaki| Oda, Nobuo| Yoda, Tadao| Kiyama, Takashi|
抄録 <p>1. The objective of this investigation was to test the influence of mammary cancer tissue extract on the induction of various tumors by urethan. Three strains of female mice, Balb/c, Zb and Db, were used in this experiment. 2. It was found that urethan was a multipotential carcinogen in the induction of (a) lung tumor, ovarian hemorrhagic cyst, and hemorrhagic lesions in various tissue in Balb/c mice, (b) lung tumor, hepatoma, leukemia, mammary cancer, Harderian gland tumor and hemorrhagic lesions in various tissues such as spleen, mesenteric lymphnode, liver and ovary in Zb strain, and (c) lung tumor, mediastinal lymphoma, leukemia, hepatoma and hemorrhagic lesions in the liver and ovary in Db mice. 3. Mammary cancer tissue extract seemed to have a promotive effect on the generalization of the mediastinal lymphoma induced by urethan in Db female mice.</p>
Amo Type Article
発行日 1962-10
出版物タイトル Acta Medicinae Okayama
16巻
5号
出版者 Okayama University Medical School
開始ページ 253
終了ページ 264
NCID AA00041342
資料タイプ 学術雑誌論文
言語 English
論文のバージョン publisher
査読 有り
NAID 120002312307
JaLCDOI 10.18926/AMO/31900
フルテキストURL fulltext.pdf
著者 Oda, Nobuo| Ida, Noriaki|
抄録 <p>1) The influence of thyroid secretion upon the induction of leukemia in Dba/2 male mice by methylcholanthrene was investigated. Radiothyroidectomy significantly reduced the incidence of leukemia in these mice. This reduction in incidence did not occur if radiothyroidectomy was performed after the administration of the carcinogen. 2) Data indicated that hypothyroidism following radiothyroidectomy interfered with the initiation rather than the promotion of methylcholanthrene- induced-Ieukemogenesis. 3) No correlation between incidence of leukemia and body weights in the mice was noted.</p>
Amo Type Article
発行日 1960-04
出版物タイトル Acta Medicinae Okayama
14巻
1号
出版者 Okayama University Medical School
開始ページ 14
終了ページ 21
NCID AA00041342
資料タイプ 学術雑誌論文
言語 English
論文のバージョン publisher
査読 有り
NAID 120002312534