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ID 32035
JaLCDOI
フルテキストURL
Thumnail fulltext.pdf 1.32 MB
著者
Miyoshi, Akira Okayama University
Makino, Hirofumi Okayama University
Hiramatsu, Makoto Okayama University
Takahashi, Kayo Okayama University
Yamane, Yukio Okayama University
Takahara, Jiro Okayama University
Suzuki, Shinya Okayama University
Ota, Zensuke Okayama University
Ofuji, Tadashi Okayama University
Takehisa, Yoshiaki Tottori City Hospital
抄録

A 26-year-old female with Bartter's syndrome associated with Graves' disease is reported. This patient had a history of Graves' disease from the age of 22 and anti-thyroid drug (Methimazole) had been administered for 2 years. Thyroid function returned to normal but general fatigue and polyuria continued. Hypokalemia was diagnosed at 25 years of age and she was referred to our hospital for evaluation. Blood pressure was normal and laboratory data revealed normal thyroid function, hypokalemic alkalosis, high plasma renin activity and high plasma aldosterone concentration. She showed normal pressor sensitivity to norepinephrine infusion, grossly diminished pressor sensitivity to exogenous angiotensin II infusion compared with the normal. A renal biopsy specimen showed juxtaglomerular cell hyperplasia. Electron microscopy confirmed lacis cell (agranular cell) proliferation.

キーワード
Bartter's syndrome
juxtaglomerular cell hyperplasia
secondary aldosteronism
plasma renin activity
Amo Type
Article
発行日
1979-08
出版物タイトル
Acta Medica Okayama
33巻
4号
出版者
Okayama University Medical School
開始ページ
305
終了ページ
314
ISSN
0386-300X
NCID
AA00508441
資料タイプ
学術雑誌論文
言語
English
論文のバージョン
publisher
査読
有り
PubMed ID