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ID 31132
JaLCDOI
フルテキストURL
著者
Fujiwara, Takuzo Center for Adult Diseases
Sakagami, Kenichi Center for Adult Diseases
Saito, Shinya Center for Adult Diseases
Uda, Masashi Okayama University
Orita, Kunzo Okayama University
抄録

The antidonor immune response was examined in a one haplotype-mismatched renal transplant recipient with an allograft that had been well-functioning for more than 10 years. Although the relative response of the mixed lymphocyte reaction (MLR) was (45.8)% and the MLR responder cells stimulated by donor cells produced measurable amounts of interleukin-2 (IL-2) (11.6 U/ml), the cytotoxic T lymphocytes (CTL) could not be generated against donor cells, even with exogenous IL-2. These results indicate that antidonor CTL precursors were either deleted or inactivated in this recipient.

キーワード
renal transplantation
long-term stable recipient
cytotoxic T lymphocytes
Amo Type
Article
発行日
1994-02
出版物タイトル
Acta Medica Okayama
48巻
1号
出版者
Okayama University Medical School
開始ページ
63
終了ページ
65
ISSN
0386-300X
NCID
AA00508441
資料タイプ
学術雑誌論文
言語
English
論文のバージョン
publisher
査読
有り
PubMed ID
Web of Sience KeyUT