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ID 52810
フルテキストURL
著者
Tomofuji, Takaaki Okayama Univ, Sch Med Dent & Pharmaceut Sci, Dept Prevent Dent
Kawabata, Yuya Okayama Univ, Sch Med Dent & Pharmaceut Sci, Dept Prevent Dent
Kasuyama, Kenta Okayama Univ, Sch Med Dent & Pharmaceut Sci, Dept Prevent Dent
Endo, Yasumasa Okayama Univ, Sch Med Dent & Pharmaceut Sci, Dept Prevent Dent
Yoneda, Toshiki Okayama Univ, Sch Med Dent & Pharmaceut Sci, Dept Prevent Dent
Yamane, Mayu Okayama Univ, Sch Med Dent & Pharmaceut Sci, Dept Prevent Dent
Azuma, Tetsuji Okayama Univ, Sch Med Dent & Pharmaceut Sci, Dept Prevent Dent
Ekuni, Daisuke Okayama Univ, Sch Med Dent & Pharmaceut Sci, Dept Prevent Dent
Morita, Manabu Okayama Univ, Sch Med Dent & Pharmaceut Sci, Dept Prevent Dent
抄録
Oxidative damage is involved in age-related inflammatory reactions. The anti-oxidative effects of hydrogen-rich water suppress oxidative damage, which may aid in inhibiting age-related inflammatory reactions. We investigated the effects of drinking hydrogen-rich water on aging periodontal tissues in healthy rats. Four-month-old male Fischer 344 rats (n = 12) were divided into two groups: the experimental group (hydrogen-rich water treatment) and the control group (distilled water treatment). The rats consumed hydrogen-rich water or distilled water until 16 months of age. The experimental group exhibited lower periodontal oxidative damage at 16 months of age than the control group. Although protein expression of interleukin-1 beta did not differ, gene expression of Nod-like receptor protein 3 inflammasomes was activated in periodontal tissues from the experimental group as compared with the control group. Drinking hydrogen-rich water is proposed to have anti-aging effects on periodontal oxidative damage, but not on inflammatory reactions in healthy rats.
発行日
2014-07-02
出版物タイトル
Scientific Reports
4巻
ISSN
2045-2322
資料タイプ
学術雑誌論文
言語
English
著作権者
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論文のバージョン
publisher
査読
有り
DOI
Web of Sience KeyUT