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ID 55311
JaLCDOI
フルテキストURL
Thumnail 71_4_341.pdf 3.74 MB
著者
Yamazaki, Kenji Department of Epidemiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Wakabayashi, Hiroshi Department of Rheumatology, Okayama City Hospital
Suganami, Yu Department of General Internal medicine, Okayama City Hospital
Sano, Shinichi Department of General Internal medicine, Okayama City Hospital
Wakunami, Yu Department of General Internal medicine, Okayama City Hospital
Katayama, Takashi Department of General Internal medicine, Okayama City Hospital
Deguchi, Kentaro Department of Neurology, Okayama City Hospital
Nagotani, Shoko Department of Neurology, Okayama City Hospital
Kishida, Masayuki
抄録
We report a case of a woman with typical dermatomyositis (DM) with skin manifestations, severe myalgia and muscle weakness complicated by interstitial lung disease (ILD) and pneumomediastinum. Pneumomediastinum persisted despite treatment with immunosuppressive therapy (steroids and cyclosporine). After the test for anti-melanoma differentiation-associated gene 5 (MDA5) antibody came out positive, we doubled the cyclosporine dose and her condition improved. Despite typical clinical features of DM, in cases complicated by pneumomediastinum or steroid resistance, measurement of anti-MDA5 antibody may be useful for immunosuppressant dose titration.
キーワード
dermatomyositis
anti-melanoma differentiation-associated gene 5 antibody
interstitial lung disease
pneumomediastinum
Amo Type
Case Report
発行日
2017-08
出版物タイトル
Acta Medica Okayama
71巻
4号
出版者
Okayama University Medical School
開始ページ
341
終了ページ
344
ISSN
0386-300X
NCID
AA00508441
資料タイプ
学術雑誌論文
言語
English
著作権者
CopyrightⒸ 2017 by Okayama University Medical School
論文のバージョン
publisher
査読
有り
PubMed ID