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ID 31898
フルテキストURL
著者
Yamamoto, Michio Okayama University
Tanimoto, Junichi Okayama University
Kojima, Sumikazu Okayama University
Nobuki, Shigeo Okayama University
Hagitani, Akira Okayama University
Iguchi, Yoshiko Okayama University
Akagi, Eiko Okayama University
Ofuji, Tadashi Okayama University
Asaka, Takakazu Okayama University
Kamura, Junta Okayama University
Shibata, Tsuneo Okayama University
抄録

The unsaturated fatty acid fraction extracted from the liver of rabbit irradiated with X-rays exerts a strong cytotoxic effect on human coelothelioma cells and Yoshida sarcoma cells both in vitro and in vivo. The cell damage seems to initiate at the nucleus, finally leading to the complete cytolysis. The inhibiting effect of this substance on the mitosis of Yoshida sarcoma cells can be observed, especially marked from prophase up to metaphase giving almost the same results obtained after X-ray irradiation. From these results and the observations reported by several authors on the cell damage by X-ray irradiation, weshould call special attention to the fact that the essential mechanism of X-ray irradiation can be attributed to the cell toxin produced after the irradiation.

発行日
1960-04
出版物タイトル
Acta Medicinae Okayama
14巻
1号
出版者
Okayama University Medical School
NCID
AA00041342
資料タイプ
学術雑誌論文
言語
English
論文のバージョン
publisher
査読
有り
Amo Type
Article
Submission Path
amo/vol14/iss1/6