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ID 31928
JaLCDOI
フルテキストURL
著者
Sakagami, Kenichi Okayama University
Miyazaki, Masashi Okayama University
Matsuoka, Junji Okayama University
Shiozaki, Shigehiro Okayama University
Saito, Shinya Okayama University
Orita, Kunzo Okayama University
抄録

An artificial liver support system for plasma exchange and plasma perfusion through BR-601 resin using a membrane separator was applied to 5 patients with postoperative liver failure. Percent absorption of total and direct bilirubin, and of bile acids were 77.1 +/- 6.4, 78.4 +/- 6.1, and 93.4 +/- 3.6%, respectively, when 250 ml of plasma was treated. Percent reductions in total and direct bilirubin, and in bile acids were 24.5 +/- 5.8, 25.5 +/- 5.8 and 30.9 +/- 8.5%, respectively. In contrast, percent reductions in total and direct bilirubin, and in bile acids by plasma exchange were 30.9 +/- 13.3, 34.5 +/- 12.5 and 24.2 +/- 8.5%, respectively. The coma grade was improved in 4 out of 5 cases, but unfortunately the patients did not recover. In conclusion, plasma perfusion through BR-601 resin is expected to play a promising role in artificial liver support systems because of its capacity to absorb bilirubin and bile acids.

キーワード
anion exchange resin (BR-601)
postoperative liver failure
artificial liver support
Amo Type
Article
発行日
1986-10
出版物タイトル
Acta Medica Okayama
40巻
5号
出版者
Okayama University Medical School
開始ページ
249
終了ページ
255
ISSN
0386-300X
NCID
AA00508441
資料タイプ
学術雑誌論文
言語
English
論文のバージョン
publisher
査読
有り
PubMed ID
Web of Sience KeyUT