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ID 14459
Eprint ID
14459
フルテキストURL
Thumnail 104_511.pdf 289 KB
タイトル(別表記)
Haptoglobin and carcinoma of uterine cervix
著者
遠藤 節夫 岡山大学医学部産科婦人科学教室
抄録
Haptoglobin is commonly known as a hemoglobin binding protein, and is an acute phase protein. Haptoglogin increases in inflammation and cancer, and acts as an immunosupressive agent. The relationship between serum haptoglobin and clinical staga and prognosis was studied in 127 uterine carcinoma patients. The haptoglobin level increased in relation to the clincal stage. Abnormal haptoglobin levels (mean+2SD or more) were studied in 127 patients. They were found in 0/37 cases (0.0%) in stage Ⅰ, 2/48(4.2%) in stage Ⅱ, 9/31(29.0%) in stage Ⅲ and 7/11 (63.6%) in stage Ⅳ(p<0.0001). Sixteen cases with abnormal haptoglobin level found in stages Ⅲ and Ⅳ, and eight cases (50.0%) died within one year. Twenty-six cases with a normal haptoglobin level were found in stages Ⅲ and Ⅳ. Only one case (3.8%) died within one year. The clinical stage ia a most important prognostic factor. However, the cases with an abnormal haptoglobin level had poor prognosis within one year in this study. Determination of the haptoglogin level prior to treatment will be useful for the selection of the high risk group of carcinoma of uterine cervix.
キーワード
ハプトグロビン
子宮頚癌
発行日
1992
出版物タイトル
岡山医学会雑誌
出版物タイトル(別表記)
Journal of Okayama Medical Association
104巻
5-6号
出版者
岡山医学会
出版者(別表記)
Okayama Medical Association
開始ページ
511
終了ページ
516
ISSN
0030-1558
NCID
AN00032489
資料タイプ
学術雑誌論文
オフィシャル URL
https://www.jstage.jst.go.jp/article/joma1947/104/5-6/104_5-6_511/_article/-char/ja/
関連URL
http://www.okayama-u.ac.jp/user/oma/index.html
言語
Japanese
著作権者
岡山医学会
論文のバージョン
publisher
査読
有り
Eprints Journal Name
joma