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ID 49161
フルテキストURL
タイトル(別表記)
Effects of Sex-steroid Hormones on Lymphocyte Genesis in the Central Lymphoid Organs of Chickens
著者
近藤 康博 岡山大学
抄録
Lymphocytes play essential roles as a kind of leukocyte in the defense mechanism of animals against infectious factors. Lymphocytes are classified into two subsets, T lymphocytes and B lymphocytes in mammals or avian species. In avian species, T lymphocytes differentiate and proliferate in the thymus which is a central lymphoid organ common to mammalians and avian species, whereas on the other hand, B lymphocytes have been known to occur in the bursa of Fabricius (bursa) which is a unique central lymphoid organ of birds. Steroid hormones, such as androgen and estrogen, have been reported to change differentiations and proliferations of these lymphocytes in corresponding lymphoid organs, indicating steroid hormones give influence lymphocyte development positively or negatively in the bursa and thymus of birds. Studying the relation between steroid hormones and lymphocyte development in the central lymphoid organs is important, because changes in the lymphocyte genesis in central organs of birds may result in altered levels of antibody production and immune functions related to T lymphocyte activity. We have studied effects of androgen and estrogen on lymphocyte differentiation and proliferation in the central lymphoid organs of chicken at Okayama University since the 1980s. In the present report, the results of these studies are summarized.
キーワード
lymphocyte
steroid hormone
bursa of Fabricius
thymus
備考
総合論文 (Monograph)
発行日
2013-02-01
出版物タイトル
岡山大学農学部学術報告
出版物タイトル(別表記)
Scientific Reports of the Faculty of Agriculture Okayama University
102巻
出版者
岡山大学農学部
出版者(別表記)
Faculty of Agriculture, Okayama University
開始ページ
43
終了ページ
51
ISSN
2186-7755
資料タイプ
紀要論文
言語
Japanese
論文のバージョン
publisher
査読
無し
Eprints Journal Name
srfa