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ID 18063
Eprint ID
18063
フルテキストURL
Thumnail 79_655.pdf 578 KB
タイトル(別表記)
Histochemical Studies of Hydrolytic Enzymes and Dehydrogenases in the Human Gastric Cancers Part Ⅱ. Analysis from the Patient Clinical Findings
著者
竹内 鬼三郎 岡山大学医学部第1外科教室
抄録
Histochemical analysis of enzyme activities of thirteen enzymes in operated stomachs of 100 patients were compared with their clinical findings. Materials and methods of histochemical analysis were the same as the previous report. Enzyme activities in the stomach cancer cells of the patients, who showed serum hypoproteinemia, decrease of blood hemoglobin content, and increase of erthrocyte sedimentation rate, were stronger than those in the patients who had normal level of the above tests. While the relationship between enzyme activities in the stromal elements and the values of clinical tests in those groups showed the reverse tendency. No parallel relationships were observed between the alkaline phosphatase activity in cancer cells and the serum alkaline phosphatase level. Also no correlation between alkaline phosphatase activity in tumor cells and the patients liver dysfunction or liver metastasis. Leucine aminopeptidase was positive in the cancer cells of 35 per cent cases. Generally, the stomach cancers removed from anacidity or hypoacidity patients had a stronger activity of this enzyme than that of normoacidity patients. In general, enzyme activities were decreased in both of the stomach cancer cells and stromal elements obtained from the preoperatively treated with antitumor agents, such as Mitomycin C, Chromomycin A(3), and Cyclohosphamide than those from non-treated oncs. The patients who showed stronger activities in stromal elements showed distinctly a better prognosis than those weaker activities. While the patients who had stronger activities in cancer cells had worse prognosis than those weaker activities.
発行日
1967-08-30
出版物タイトル
岡山医学会雑誌
出版物タイトル(別表記)
Journal of Okayama Medical Association
79巻
7-8号
出版者
岡山医学会
出版者(別表記)
Okayama Medical Association
開始ページ
655
終了ページ
662
ISSN
0030-1558
NCID
AN00032489
資料タイプ
学術雑誌論文
オフィシャル URL
https://www.jstage.jst.go.jp/article/joma1947/79/7-8/79_7-8_655/_article/-char/ja/
関連URL
http://www.okayama-u.ac.jp/user/oma/
言語
Japanese
著作権者
岡山医学会
論文のバージョン
publisher
査読
有り
Eprints Journal Name
joma