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ID 17552
Eprint ID
17552
フルテキストURL
Thumnail 85_129.pdf 413 KB
タイトル(別表記)
Effects of Irradiation on Lipid Peroxidation in Rat Organs.Part Ⅰ. Effects of whole body irradiation on lipid peroxide formation in rat organs.
著者
渡辺 節生 岡山大学医学部放射線医学教室
抄録
After the whole body X-irradiation (650R) of rats, the lipid peroxide formation of various organs were estimated by the TBA reaction, and the results are presented as follows: (1) In TBA reaction tests on the lipid peroxidation in the liver, heart, spleen and kidney with homogenates being incubated, the TBA value were slightly high with endogenous homogenates, but on the addition of Fe(++) the reaction was further accelerated markedly. With liver and kidney that showed a high reaction on addition of Fe(++), the reaction was similarly accelerated on addition of ascorbic acid, but with heart and spleen the reaction at initial stage did not show any significant difference from that of the group without any addition. (2) In every organ from the irradiated animal the activity of lipid peroxide formation was greater than that in organs from non-irradiated control animals. (3) TBA value in the group added with Fe(++) were higher than those in the group without any addition, suggesting that X-irradiation greatly the lipid peroxidation in organs. (4) Change in the acceleration of lipid peroxidation accompanying the irradiation appears as a shortening of reaction-induction time. (5) Radioactivity-dose dependent change can be observed only in the liver, and the time-lapse change after irradiation can also observed only in the liver. (6) These results suggest that the lipid peroxidation following the whole body X-irradiation shows a significant change primarily in the liver.
発行日
1973-04-30
出版物タイトル
岡山医学会雑誌
出版物タイトル(別表記)
Journal of Okayama Medical Association
85巻
3-4号
出版者
岡山医学会
出版者(別表記)
Okayama Medical Association
開始ページ
129
終了ページ
136
ISSN
0030-1558
NCID
AN00032489
資料タイプ
学術雑誌論文
オフィシャル URL
https://www.jstage.jst.go.jp/article/joma1947/85/3-4/85_3-4_129/_article/-char/ja/
関連URL
http://www.okayama-u.ac.jp/user/oma/
言語
Japanese
著作権者
岡山医学会
論文のバージョン
publisher
査読
有り
Eprints Journal Name
joma