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ID 40637
フルテキストURL
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タイトル(別表記)
Experimental study of optimal fat/glucose ratio for total parenteral nutrition in rats
著者
池田 昭彦 岡山大学医学部第二外科学教室
抄録
The optimal fat/glucose ratio for TPN was determined, using oxidation and distribution of (14)C labeled fat emulsion and glucose. Animals were divided into five groups according to percentage of energy supplied as fat i·e. 0%, 20%, 40%, 60% and 80%, respectively. (14)C-labeled fat emulsion and glucose were injected during TPN and the rate of oxidation to (14)CO(2) as well as (14)C distribution in various organs were measured. Oxidation of (14)C-glucose was constant in all groups and that of (14)C-labeled fat emulsion was inversely related to the amount of glucose administered simultaneously. (14)C-distribution in adipose tissue was correlated to the amount of glucose infused. As oxidation of glucose was significantly higher than that of fat, the higher the fat content of non-protein calorie, the less oxidation was observed. The groups given 60% and 80% energy composed of fat, showed less nitrogen retention and glycogen content in liver and muscle. These two groups exhibited high blood levels of free fatty acid, cholesterol and phospholipids. These findings suggest that the optimal blending ratio of fat would be around 20-40% of the non-protein calories.
キーワード
(14)C標識化ブドウ糖
(14)C標識化脂肪乳剤
脂肪代謝
発行日
1990-06
出版物タイトル
岡山医学会雑誌
出版物タイトル(別表記)
Journal of Okayama Medical Association
102巻
5-6号
出版者
岡山医学会
出版者(別表記)
Okayama Medical Association
開始ページ
663
終了ページ
678
ISSN
0030-1558
NCID
AN00032489
資料タイプ
学術雑誌論文
オフィシャル URL
https://www.jstage.jst.go.jp/article/joma1947/102/5-6/102_5-6_663/_article/-char/ja/
関連URL
http://www.okayama-u.ac.jp/user/oma/
言語
Japanese
著作権者
岡山医学会
論文のバージョン
publisher
査読
有り
Eprints Journal Name
joma