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ID 19468
Eprint ID
19468
フルテキストURL
Thumnail 71_2261.pdf 3.02 MB
タイトル(別表記)
Clinical and Experimental Studies on the Characteristics of Idiopathic Thrombocytopenic Purpura Part 1. The Influence of the Serum of the Patient with Idiopathic Thrombocytopenic Purpura on the Megakaryocyte Function of Normal Persons
著者
本多 正憲 岡山大学医学部平木内科
抄録
With the purpose to pursue the platelet reducing factor in the serum of idiopathic thrombocytopenic purpura, the author performed the bone-marrow tissue culture of the normal persons and the patients with this disease by the simple method of bone-marrow tissue culture; and also observed number of megakaryocytes, their functions (motility and separation of platelets) in the tissue growth area, relative tissue growthrate, and the wandering velocity of neutrophils by means of the bone-marrow tissue culture of normal persons in the serum of patient with this disease. 1. In the bone-marrow tissue culture of this disease number of megakaryocytes appearing in the tissue growth area was normal in one case, and greater than the normal in two cases; but the megakaryocyte funcion was on the whole lowered. The relative growth rate and the wandering velocity of neutrophils showed no significant differences from those of the control. 2. In the case of the bone-marrow tissue culture of normal persons in the serum of this disease there was no significant difference in the number of megakryocytes appearing in the growth area from that of the control, but the megakaryocyte function was markedly diminished and also a marked degeneration was recognized. However, the relative growth rate and the wandering velocity of neutrophils showed no significant differences from those of the control. From these findings it is clear that there exists some factor in the serum of the patient with thrombocytopenic purpura, which acts directly on megakarycoytes so as to inhibit the thrombocyte production.
発行日
1959-04-15
出版物タイトル
岡山医学会雑誌
出版物タイトル(別表記)
Journal of Okayama Medical Association
71巻
5-1号
出版者
岡山医学会
出版者(別表記)
Okayama Medical Association
開始ページ
2261
終了ページ
2270
ISSN
0030-1558
NCID
AN00032489
資料タイプ
学術雑誌論文
オフィシャル URL
https://www.jstage.jst.go.jp/article/joma1947/71/5-1/71_5-1_2261/_article/-char/ja/
関連URL
http://www.okayama-u.ac.jp/user/oma/
言語
Japanese
著作権者
岡山医学会
論文のバージョン
publisher
査読
有り
Eprints Journal Name
joma