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ID 17068
Eprint ID
17068
フルテキストURL
Thumnail 92_629.pdf 228 KB
タイトル(別表記)
Inverse relationship between heart rate and myocardial oxygen consumption per beat
著者
原岡 昭一 岡山大学医学部第一内科教室
斉藤 大治 岡山大学医学部第一内科教室
庵谷 和夫 岡山大学医学部第一内科教室
長花 晴樹 岡山大学医学部第一内科教室
藤井 章伸 岡山大学医学部第一内科教室
間嶋 行造 岡山大学医学部第一内科教室
抄録
Relationship between heart rate and myocardial oxygen consumption per beat was studied in anesthetized open-chest dogs. Myocardial oxygen consumption per minute (MVO(2)) was calculated as the product of the left coronary artery blood flow and coronary arterio-venous oxygen difference. Myocardial oxygen consumption per beat (MVO(2)-Beat) was the quotient of MVO(2) divided by heart rate (HR). HR was varied in 78-210 beats/min with left atrial pacing. Systemic arterial and left ventricular enddiastolic pressure were kept constant, and arterial blood gases were within physiological ranges. Although MVO(2) correlated significantly with HR (r=0.71), MVO(2)-Beat decreased in association with an increase in heart rate. Closer relationship was observed between MVO(2)-Beat and HR; MVO(2)-Beat (ml/100g LV muscle)= -0.00036 + 0.13, r= -0.86, P<0.001. As the results, MVO(2) was represented as a quadratic equation of HR; MVO(2) (ml/min/100g LV muscle)= -0.00036HR(2) + 0.13HR. There was a good correlation (r=0.88) between MVO(2)-Beat and the area under a stroke left ventricular pressure curve. This finding and constant systemic arterial and left ventricular pressure suggest that the inverse relationship between MVO(2)-Beat and HR is mainly due to a reduction in duration of systolic left ventricular wall tension.
キーワード
心拍数
心筋酸素消費量
左室内圧
収縮時間
発行日
1980-06-30
出版物タイトル
岡山医学会雑誌
出版物タイトル(別表記)
Journal of Okayama Medical Association
92巻
5-6号
出版者
岡山医学会
出版者(別表記)
Okayama Medical Association
開始ページ
629
終了ページ
633
ISSN
0030-1558
NCID
AN00032489
資料タイプ
学術雑誌論文
オフィシャル URL
https://www.jstage.jst.go.jp/article/joma1947/92/5-6/92_5-6_629/_article/-char/ja/
関連URL
http://www.okayama-u.ac.jp/user/oma/index.html
言語
Japanese
著作権者
岡山医学会
論文のバージョン
publisher
査読
有り
Eprints Journal Name
joma