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ID 41268
フルテキストURL
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タイトル(別表記)
Experimental Studies on the Influence of γ-Amino-β-Hydroxybutyric Acid upon the Metabolism in Rabbit Brain after Cardiazol Convulsion Part 1. Infuence of γ-Amino-β-Hydroxybutyric Acid upon the Free Amino Acid Nitrogen Content and Choliesterase Activity in Cerebral Cortex of Rabbits after Metrazcl Convulsion
著者
川上 裕 岡山大学医学部第1(陣内)外科教室
抄録
The influences of GABOB (γ-amino-β-hydroxybutric acid) upon free amino acid content and ChE activity in cerebral cortex of normal rabbits and those of rabbits after metrazol convulsin were studied. 1) After the injection of 100 mg GABOB, free amino acid nitrogen decreases temporary. Also after that of 10 mg GABOB, it shows a slight decrease. 2) During metrazol convulsion, free amino acid nitrogen content decreases markedly. 3) The intravenous injection of 100 mg GABOB before metrazol convulsion does not influence the variation of free amino acid nitrogen content during convulsion. Positively after that of 10 mg, the decrease of free amino acid nitrogen content by cardiazol convulsion is restrained slightly. 4) By intravenous injection of 100 mg GABOB., ChE activity is accelerated but by that of 10 mg, it is rather restrained. 5) During convulsion, the ChE activity in cerebral cortex decreases markedly. 6) In this case, if 100 mg GABOB is given intravenously before the intravenous injection of metrazol, in the maximum stadium of convulsion antagonistic function is fairly found, but in the latter stadium of convultion it is scarcely influenced. In case of 10 mg GABOB intravenous injection, ChE activity decreases by metrazol convulsion while it shows no sign of being influenced in the maximum stadium of convulsion.
発行日
1959-10-20
出版物タイトル
岡山医学会雑誌
出版物タイトル(別表記)
Journal of Okayama Medical Association
71巻
11-1号
出版者
岡山医学会
出版者(別表記)
Okayama Medical Association
開始ページ
7305
終了ページ
7315
ISSN
0030-1558
NCID
AN00032489
資料タイプ
学術雑誌論文
オフィシャル URL
https://www.jstage.jst.go.jp/article/joma1947/71/11-1/71_11-1_7305/_article/-char/ja/
関連URL
http://www.okayama-u.ac.jp/user/oma/
言語
Japanese
著作権者
岡山医学会
論文のバージョン
publisher
査読
有り
Eprints Journal Name
joma