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ID 18842
Eprint ID
18842
フルテキストURL
Thumnail 73_515.pdf 693 KB
タイトル(別表記)
Experimental Studies on Sideroblasts Part 2 Effects of Iron and Cobalt on Sideroblasts In Vitro in Experimental Anemia
著者
山内 泰助 岡山大学医学部平木内科
抄録
By adding iron or cobalt to the tissne culture in fluid medium of bone marrow from normal and various experimental anemic rabbits the author has observed the alteration in the number of sideroblasts and studied the iron metabolism of erythroblasts. The following are the results. 1. In the case of the bone-marrow tissue culture of normal rabbit supplemented with iron sideroblasts are slightly increased in number. 2. In the case of bensol or collargol anemia hardly any increase can be recognized in sideroblasts by the iron addition. 3. In the case of the rabbit irradiated with 300r. the addition of iron increases sideroblasts in number considerably. 4. In the case of hemorrhagic anemia the addition of iron markedly increases the number of sideroblasts as the iron deficiency state advances in its degree. 5. Hardly any increase in the sideroblast number can be observed in the case of phenylhydrazine anemia supplemented with iron. 6. From these alterations in siderodlasts by the effect of iron addition, it is assumed that non-hemoglobin iron in erythroblasts has an important bearing on the iron uptake of erythroblasts. 7. Cobalt has an action as to direct the iron in erythroblasts towards the heme synthesis because in the case supplemented with iron plus cobalt the increase in the number of sideroblasts is smaller than that supplemented with iron alone.
発行日
1961-09-30
出版物タイトル
岡山医学会雑誌
出版物タイトル(別表記)
Journal of Okayama Medical Association
73巻
7-9号
出版者
岡山医学会
出版者(別表記)
Okayama Medical Association
開始ページ
515
終了ページ
524
ISSN
0030-1558
NCID
AN00032489
資料タイプ
学術雑誌論文
オフィシャル URL
http://www.journalarchive.jst.go.jp/japanese/jnlabstract_ja.php?cdjournal=joma1947&cdvol=73&noissue=7-9&startpage=515
関連URL
http://www.okayama-u.ac.jp/user/oma/
言語
Japanese
著作権者
岡山医学会
論文のバージョン
publisher
査読
有り
Eprints Journal Name
joma