‰ªŽRˆãŠw‰ï Acta Medica Okayama 0030-1558 93 1-2 suppl 1981 “ú–{”]‰ŠƒEƒCƒ‹ƒXŠ´�õLLCMK2�×–E‚Ì“§‰ßŒ^“dŽqŒ°”÷‹¾‚É‚æ‚錤‹† 23 27 EN Kazuya Akatsuka Fumio Uno Naomichi Uno Ikuyo Kuroki Shigeki Yamanishi Akira Tominaga Kiyoshi Tsutsui Shiro Nii LLCMK2 cells infected with Japanese encephalitis virus were studied by transmission electron microscopy, with a special consideration on the nature of white round granules of 0.4-1.3 ƒÊm dIameter with a scanning electron microscope. Virus particles were detected in cytoplasmic vacuoles with smooth-surfaced membranes, in those with rough-surfaced membranes and also in the perinuclear space. Besides the virus-enclosing vacuolar structures many lipid droplets were observed in the cytoplasm of infected cells, although they were few in control non-infected cells. These droplets were supposed to correspond to the white granules observed by a scanning electron microscope. No potential conflict of interest relevant to this article was reported.