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ID 18076
Eprint ID
18076
フルテキストURL
Thumnail 79_733.pdf 589 KB
タイトル(別表記)
Antimitotic Action of "CORNIN" Extracted from Rabbit and Dog Organ
著者
寺坂 俊明 岡山大学医学部第一生理学教室
抄録
It is generally observed that there are various organ-specific mitotic rates in regeneration and compensatory growth. Nevertheless, each tissue can proliferate well in a suitable culture medium. These facts suggest that there are regulating substances for cell division. The author extracted an antimitotic substance "CORNIN" from rabbit and dog organs by the alcoholic fractionation, mainly from muscle layer and mucous layer of digestive organs. Each cornin of internal organs has less antimitotic effeet on sea urchin eggs than that of muscle or cornea. Furthermore, there are no difference between muscle layer and mucous layer as regards the antimitotic effect. There is no difference in the qualitative analysis of cornins for protein and sugar. Typical protein waves are shown by polarogram excepting cornin of regenerating rat liver. The ultra-violet absorption curves show the same maximum absorption peak at 260 mμ, which is the same as that of corneal cornin, but is different from muscle cornin that shows the peak at 249 mμ. The paper electrophoresis does not show any remarkable fifferences among these cornins. With respect to the cornin activity, there can be seen no remarkable difference between muscle layer and mucous layer.
発行日
1967-10-30
出版物タイトル
岡山医学会雑誌
出版物タイトル(別表記)
Journal of Okayama Medical Association
79巻
9-10号
出版者
岡山医学会
出版者(別表記)
Okayama Medical Association
開始ページ
733
終了ページ
742
ISSN
0030-1558
NCID
AN00032489
資料タイプ
学術雑誌論文
オフィシャル URL
https://www.jstage.jst.go.jp/article/joma1947/79/9-10/79_9-10_733/_article/-char/ja/
関連URL
http://www.okayama-u.ac.jp/user/oma/
言語
Japanese
著作権者
岡山医学会
論文のバージョン
publisher
査読
有り
Eprints Journal Name
joma