このエントリーをはてなブックマークに追加
ID 42860
フルテキストURL
Thumnail 67_1035.pdf 3.14 MB
タイトル(別表記)
Experimental Studies on the Pathogenicity of Echinostoma cinetorchis Heterotopic parasitism, Echinostoma cinetorchis in the Liver
著者
宗 謙治 岡山大学医学部病理学教室
抄録
In the previous paper the author reported the pathological studies on the animals affected by Echinostoma cinetorchis with some endemiological observations presenting the fundamental knowledge on the pathogenicity of this worm. The purpose of this paper is to reveal the mechanism of heterotopic parasitism of this worm and pathologic changes in the liver which have been found unexpectedly on the two cases of affected animals as introduced briefly in the previous paper. The experiments revealed the mechanism of this curious heterotopic parasitism of this intestinal parasitic trematoda, i.e. 1. Repeated feeding of metacercaria proved that this worm acutually can invide into the liver (passing through the common bile ducts) and grow in the intrahepatic ducts. 2. The feeding test proved that the worms invide more frequently into the liver of starved animals than of those of normally nurished, indicating the starvation gave a better condition for the invasion into the liver. 3. On the other hand, the massive parasitism in intestine also caused frequent intrahepatic invasion, though the massive feeding of metacercaria not always resulted in the massive intestinal parasitism. The pathologic changes seen on the attacked liver are summarized as follows. 1. The defect or desquamation of the epithelium of the bile ducts surrounding the worm body, which will be the results of mechanic injury given by the parasite. 2. Generallized cholangitis and pericholangitis which would be induced by the mechanic injury followed by bacterial infection. This was accompanied by the inflammatory changes of the parenchym and the vessels of pfortal system. 3. Focal necrosis of the liver cells caused by the secoundery induced disturbances of circulatory system which developed to the purulent foci elswhere. 4. Exsudative and proliferative inflammation on the tissues surrounding the eggs of the worm.
発行日
1955-05-31
出版物タイトル
岡山医学会雑誌
出版物タイトル(別表記)
Journal of Okayama Medical Association
67巻
5号
出版者
岡山医学会
出版者(別表記)
Okayama Medical Association
開始ページ
1035
終了ページ
1047
ISSN
0030-1558
NCID
AN00032489
資料タイプ
学術雑誌論文
オフィシャル URL
https://www.jstage.jst.go.jp/article/joma1947/67/5/67_5_1035/_article/-char/ja/
関連URL
http://www.okayama-u.ac.jp/user/oma/
言語
Japanese
著作権者
Copyright© 岡山医学会
論文のバージョン
publisher
査読
有り
Eprints Journal Name
joma