start-ver=1.4
cd-journal=joma
no-vol=67
cd-vols=
no-issue=5
article-no=
start-page=1035
end-page=1047
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1955
dt-pub=19550531
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Experimental Studies on the Pathogenicity of Echinostoma cinetorchis Heterotopic parasitism, Echinostoma cinetorchis in the Liver
kn-title=Echinostoma cinetorchisの病原性に関する実験的研究 Echinostoma cinetorchisの肝内異所寄生に就て
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=In the previous paper the author reported the pathological studies on the animals affected by Echinostoma cinetorchis with some endemiological observations presenting the fundamental knowledge on the pathogenicity of this worm. The purpose of this paper is to reveal the mechanism of heterotopic parasitism of this worm and pathologic changes in the liver which have been found unexpectedly on the two cases of affected animals as introduced briefly in the previous paper. The experiments revealed the mechanism of this curious heterotopic parasitism of this intestinal parasitic trematoda, i.e. 1. Repeated feeding of metacercaria proved that this worm acutually can invide into the liver (passing through the common bile ducts) and grow in the intrahepatic ducts. 2. The feeding test proved that the worms invide more frequently into the liver of starved animals than of those of normally nurished, indicating the starvation gave a better condition for the invasion into the liver. 3. On the other hand, the massive parasitism in intestine also caused frequent intrahepatic invasion, though the massive feeding of metacercaria not always resulted in the massive intestinal parasitism. The pathologic changes seen on the attacked liver are summarized as follows. 1. The defect or desquamation of the epithelium of the bile ducts surrounding the worm body, which will be the results of mechanic injury given by the parasite. 2. Generallized cholangitis and pericholangitis which would be induced by the mechanic injury followed by bacterial infection. This was accompanied by the inflammatory changes of the parenchym and the vessels of pfortal system. 3. Focal necrosis of the liver cells caused by the secoundery induced disturbances of circulatory system which developed to the purulent foci elswhere. 4. Exsudative and proliferative inflammation on the tissues surrounding the eggs of the worm.
en-copyright=
kn-copyright=

en-aut-name=SoKenji
en-aut-sei=So
en-aut-mei=Kenji
kn-aut-name=宗謙治
kn-aut-sei=宗
kn-aut-mei=謙治
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部病理学教室
END

start-ver=1.4
cd-journal=joma
no-vol=68
cd-vols=
no-issue=1-4
article-no=
start-page=51
end-page=58
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1956
dt-pub=1956
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=An autopsy case of Primaly leiomyosarcoma of the spermatic cord.
kn-title=睾丸部(精系下部)に原発した滑平筋肉腫の1剖検例
en-subtitle=
kn-subtitle=
en-abstract=A case of malignant myogenous tumor originated on the left spermatic cord of 49 aged man is presented. This tumor was found as a painless tumor in the testicular region about 7 years before the death of patient, and one year later it grew to a child-head sized tumor showing a rapid development. Clinically the tumor was diagnosed as a cancer of the testis and resected surgically. (Fig. 1) No metastasized tumor was recognized at that time. However, 3 years and a half later a new tumor appeared on the center of the heald wound. The relapsed tumor was resected again, but after about one year and a half a tumor reappeared on the same region (Fig. 4) accompaning with an extensive metastasis in the thoracic cavity. (Fig. 8) The patient died
by heart failure caused by the metastasized tumors. Anatomical and histopathological observations revealed that this tumor was a leiomyosarcoma originated in the lower region of the left spermatic cord. The tumor tissues consisted of whorled masses of polymorphic spindel-shaped cells with lod-shaped mucleus similar to the immature smooth muscle cells. (Fig. 9 & 7)
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=SoKenji
en-aut-sei=So
en-aut-mei=Kenji
kn-aut-name=宗謙治
kn-aut-sei=宗
kn-aut-mei=謙治
aut-affil-num=1
ORCID=

en-aut-name=YabeTadataka
en-aut-sei=Yabe
en-aut-mei=Tadataka
kn-aut-name=矢部忠孝
kn-aut-sei=矢部
kn-aut-mei=忠孝
aut-affil-num=2
ORCID=

en-aut-name=NambaYikikazu
en-aut-sei=Namba
en-aut-mei=Yikikazu
kn-aut-name=難波幸一
kn-aut-sei=難波
kn-aut-mei=幸一
aut-affil-num=3
ORCID=

en-aut-name=NoharaNosomi
en-aut-sei=Nohara
en-aut-mei=Nosomi
kn-aut-name=野原望
kn-aut-sei=野原
kn-aut-mei=望
aut-affil-num=4
ORCID=

en-aut-name=OuraIsao
en-aut-sei=Oura
en-aut-mei=Isao
kn-aut-name=大浦功夫
kn-aut-sei=大浦
kn-aut-mei=功夫
aut-affil-num=5
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学

affil-num=2
en-affil=
kn-affil=岡山大学

affil-num=3
en-affil=
kn-affil=岡山大学

affil-num=4
en-affil=
kn-affil=岡山大学

affil-num=5
en-affil=
kn-affil=岡山大学
END