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タイトル(別表記) Intracellular uptake of extracellular vesicles shed by bone marrow-derived macrophages stimulated with lactic acid bacteria in adipocyte and skeletal muscle cell line
フルテキストURL poalas_034_032.pdf
著者 鶴田 剛司| 伊藤 洋平| 西野 直樹| Teresia Aluoch Muhomah| 勝又 恵実子| 園山 慶|
備考 寄稿(Contribution)
出版物タイトル 岡山実験動物研究会報
発行日 2018-04
出版者 岡山実験動物研究会
出版者(別表記) Okayama Association for Laboratory Animal Science
開始ページ 32
終了ページ 35
資料タイプ 学術雑誌論文
言語 Japanese
論文のバージョン publisher
Eprints Journal Name poalas
タイトル(別表記) Reactivity of secretory immunoglobulin A against gut bacteria is attenuated by high-fat diet consumption
フルテキストURL poalas_035_009_011.pdf
著者 鶴田 剛司| MUHOMAH, Teresia Aluoch| 園山 慶| 西野 直樹|
抄録 Secretory immunoglobulin A (SIgA) is predominant antibody secreted into the gut relating to maintain gut homeostasis. In the present study, we focused on the SIgA coating of gut bacteria as a mucosal immune response affecting the gut bacteria following a high-fat diet (HFD). This study newly showed that the level of SIgA coating of gut bacteria was significantly decreased in HFD-fed mice than normal-fat diet (NFD)-fed mice. Furthermore, we found that the relative abundances of gut bacteria were significantly negatively or positively correlated with the level of SIgA coating of gut bacteria in NFD-fed and HFD-fed mice. Our observations suggest that a decrease in the level of SIgA coating of the gut bacteria through a HFD might relate to HFD-induced changes in bacterial composition.
出版物タイトル 岡山実験動物研究会報
発行日 2019-06
開始ページ 9
終了ページ 11
言語 Japanese
論文のバージョン publisher