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ID 17049
Eprint ID
17049
フルテキストURL
Thumnail 92_531.pdf 2.35 MB
タイトル(別表記)
Histological studies of the lung in allergic respiratory responses Part Ⅱ. Histological investigations of the lung in experimentally sensitized animals
著者
原田 寛 岡山大学医学部第2内科学教室
抄録
Hypersensitivity pneumonitis and bronchial asthma were experimentally developed with adjuvant and aerosolized antigens used together and separately. Histological investigations of the lung were performed in several conditions depending on the use of adjuvant or antigens. The results were as follows. 1) In animals treated with BCG only, pulmonary histological findings such as granulomatous changes, small clusters of mononuclear cell accumulation, interstitial mononuclear cell infiltration and septal thickening were observed. Granulomatous changes in the condition consisted of predominant epithelioid cells. 2) In animals sensitized by aerosolized antigens only, marked histological changes such as cell infiltration around the alveolar septum and bronchiolar wall were observed in the use of Candida antigen. On the other hand, granuloma formation and cell infiltration around vascular wall were predominantly found in the use of Aspergillus antigens. 3) The incidence of granuloma formation and the degree of mononuclear cell infiltration tended to increase with the use of high concentration of antigen. 4) Histological findings such as granulomatous changes and cell infiltration were marked in the animals sensitized by both adjuvant and antigens.
キーワード
BCG
カンジダ
アスペルギルス
肉芽腫
実験的過敏性肺臓炎
発行日
1980-04-30
出版物タイトル
岡山医学会雑誌
出版物タイトル(別表記)
Journal of Okayama Medical Association
92巻
3-4号
出版者
岡山医学会
出版者(別表記)
Okayama Medical Association
開始ページ
531
終了ページ
544
ISSN
0030-1558
NCID
AN00032489
資料タイプ
学術雑誌論文
オフィシャル URL
https://www.jstage.jst.go.jp/article/joma1947/92/3-4/92_3-4_531/_article/-char/ja/
関連URL
http://www.okayama-u.ac.jp/user/oma/index.html
言語
Japanese
著作権者
岡山医学会
論文のバージョン
publisher
査読
有り
Eprints Journal Name
joma