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ID 16823
Eprint ID
16823
フルテキストURL
Thumnail 94_599.pdf 1.84 MB
タイトル(別表記)
Lymphoid infiltration of the primary tumor in gastric cancer
著者
北川 尭之 岡山大学医学部第一外科教室
抄録
The correlation among lymphoid infiltration (LI) in the primary tumor, cell-mediated immunity and the accumulative 5-year survival rate was studied in 515 patients with resected gastric cancer. As scales of cell-mediated immunity, the blastformation rate of peripheral lymphocytes against phytohemagglutinin (PHA)-M (Difco) and the PPD skin reaction were examined. The results were as follows: 1) LI of the primary tumor was found in 124 out of 515 patients (24.1%); patients with marked LI were 6.4%. 2) The blastformation rate in patients with positive LI was significantly higher than that in patients with negative LI (p<0.01). 3) The LI of the primary tumor tended to be found commonly in patients with gastric cancer in clinical stage I. 4) The blastformation rate decreased when the clinical stage of gastric cancer progressed, however, this trend was not seen in patients with positive LI regardless of the stage. 5) The accumulative 5-year survival rate in patients with positive LI was longer than that in the patients with LI negative (p<0.05). 6) There was no relationship among the degrees of LI in the primary tumor, the PPD skin reaction and lymphocyte count. In conclusion, LI of the primary tumor has a close relationship with the blastformation rate, and this phenomenon suggests that a local appearance of cell-mediated immunity in the cancer bearing body may occur.
キーワード
胃癌
lymphoid infiltration
リンパ球PHA幼若化率
PPD反応
生存率
発行日
1982-08-30
出版物タイトル
岡山医学会雑誌
出版物タイトル(別表記)
Journal of Okayama Medical Association
94巻
7-8号
出版者
岡山医学会
出版者(別表記)
Okayama Medical Association
開始ページ
599
終了ページ
612
ISSN
0030-1558
NCID
AN00032489
資料タイプ
学術雑誌論文
オフィシャル URL
https://www.jstage.jst.go.jp/article/joma1947/94/7-8/94_7-8_599/_article/-char/ja/
関連URL
http://www.okayama-u.ac.jp/user/oma/index.html
言語
Japanese
著作権者
岡山医学会
論文のバージョン
publisher
査読
有り
Eprints Journal Name
joma