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ID 18892
Eprint ID
18892
フルテキストURL
Thumnail 73_687.pdf 17.2 MB
タイトル(別表記)
Effects of β-Hydroxyglutamic Acid (β-OH-GA) on the Metabolism of the Perfused Cat Brain.
著者
丸川 尚一 岡山大学医学部神経精神医学教室
抄録
The perfusion of the cat brain was performed according to the method of Ikeda, H. who modified the method of Geiger, A.. Electrocorticographical, biochemical and pharmacological findings in the case of the administration of β-OHGA were obtained, and then the correlation of their appearances were investigated. 1). Electrocorticogram of the perfused cat brain was activated by the administration of β-OH-GA. 2). Following the activation of electrocorticogram, all reflexes as conjuctival, corneal reflexes, pupillary reactions and pain sensation were activated, and then spontanous body movement appeared at the same time. 3). Cerebral blood flow rate, oxygen and glcose consumption, lactic acid liberation were all increased. 4). The changes as above were reversible and soon recovered again by the perfusion without β-OH-GA. 5). Electrocorticogram and respiration rate did not showed any alteration. And, changes of blood pressure showed different case by case and represented not determinated tendency. 6). Any significant difference between effects of threo-type and erythro-type of β-OH-GA on the perfused cat brain was not observed.
発行日
1961-09-30
出版物タイトル
岡山医学会雑誌
出版物タイトル(別表記)
Journal of Okayama Medical Association
73巻
7-9号
出版者
岡山医学会
出版者(別表記)
Okayama Medical Association
開始ページ
687
終了ページ
696
ISSN
0030-1558
NCID
AN00032489
資料タイプ
学術雑誌論文
オフィシャル URL
https://www.jstage.jst.go.jp/article/joma1947/73/7-9/73_7-9_687/_article/-char/ja/
関連URL
http://www.okayama-u.ac.jp/user/oma/
言語
Japanese
著作権者
岡山医学会
論文のバージョン
publisher
査読
有り
Eprints Journal Name
joma